CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1744
Family Name Cannabinoid receptor 1 ligand AGN-PC-04YSUM family
No. of Seeds 7 No. of Other Members 6
Family Centroid CFAMM00327051 Functional Category Bioactive with Natural Product
Superfamily Integrin beta-2 and P2X purinoceptor 7 Binder Superfamily
Class Class 1340

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
Cannabinoid receptor 1 Ligand Rimonabant Family 20 260
Histidine decarboxylase Inhibitor Bf-derm1 Family 12 95
Glycogen phosphorylase, muscle form Inhibitor PSN357 Family 3 253
Neuromedin-K receptor Ligand SB222200 Family 17 235
Cholecystokinin receptor type A Ligand Tarazepide Family 6 323
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
Reverse transcriptase Inhibitor IDX899 Family 2 118
Cannabinoid receptor 1 Ligand TM38837 Family 20 15
Setipiprant family 5 118
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 93
Cannabinoid receptor 2 Ligand JWH-204 Family 6 10
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Microsomal triglyceride transfer protein large subunit Inhibit... 5 9
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
Adenosine receptor A3 and Potassium voltage-gated channel subf... 1 18
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Acetylcholinesterase and Cholinesterase Inhibitor 7-oxo-7h-dib... 2 3
Acetylcholinesterase and Cholinesterase Inhibitor 3-(2-diethyl... 12 160
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
Substance-P receptor ligand AGN-PC-01ZIXQ family 13 42
Huntingtin and Glycogen synthase kinase-3 beta inhibitor SB 21... 2 4
RAC-alpha serine/threonine-protein kinase and Cyclin-dependent... 3 7
5-hydroxytryptamine receptor 2A and Sodium-dependent serotonin... 1 10
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 3 59
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 8 16
Cellular tumor antigen p53 inhibitor CHEMBL1418224 family 1 62
Translocator protein inhibitor (2E)-N-(4-chlorophenyl)-N-methy... 2 13
cGMP-specific 3',5'-cyclic phosphodiesterase and Dual 3',5'-cy... 4 129
Ceramide glucosyltransferase inhibitor AGN-PC-07YS0C family 4 3
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor 2-... 18 2
Cannabinoid receptor 1 ligand 5-cyano-1-[(3,5-dichlorophenyl)m... 2 0
Substance-P receptor and Neuromedin-K receptor ligand SureCN88... 4 14
Cannabinoid receptor 1 ligand 5-(4-chlorophenyl)-1-(2,4-dichlo... 2 19
Cannabinoid receptor 1 ligand 5-(4-chlorophenyl)-1-(2,4-dichlo... 1 0
Coagulation factor X and Prothrombin inhibitor 2-carboxyindole... 2 8
Poly [ADP-ribose] polymerase 1 inhibitor CHEMBL186461 family 2 4
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor 2-... 3 0
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor 3-... 3 6
Translocator protein inhibitor N-(4-chlorophenyl)-N-methyl-2-(... 2 0
Cannabinoid receptor 1 ligand (2-cyclopentyl-5-prop-2-enyl-3,4... 3 8
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-009GH... 8 10
Cannabinoid receptor 1 ligand SureCN4819820 family 11 5
Histone deacetylase 6 and Histone deacetylase 1 inhibitor 4-[(... 2 9
Lysosomal Pro-X carboxypeptidase inhibitor [(3S,4R)-1-tert-but... 20 13
Coagulation factor X inhibitor SureCN8169809 family 12 18
Substance-P receptor ligand SureCN7796965 family 9 1
Melanin-concentrating hormone receptor 1 ligand SureCN4261878 ... 4 7
Cathepsin K inhibitor (1R,2R)-2-(6-chloro-1,3,4,5-tetrahydropy... 2 0
Cannabinoid receptor 1 ligand SureCN4454684 family 2 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 8 6
Coagulation factor X inhibitor 3-chloro-N-[(1S,2S)-2-[[4-(2-ox... 22 3
Gonadotropin-releasing hormone receptor ligand 1-adamantyl-[2-... 3 1
Seprase and Prolyl endopeptidase inhibitor 7-chloro-N-[2-[(2S)... 3 3
Acetylcholinesterase inhibitor N-[6-[4-[(6-chloro-1,2,3,4-tetr... 9 0
C-C chemokine receptor type 5 ligand 6-chloro-N-[(3R)-3-[4-[(5... 16 4
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor 3-... 17 0
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 3 5
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 3 8
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 4 11
Substance-P receptor ligand AGN-PC-004REJ family 3 0
Cannabinoid receptor 1 ligand AGN-PC-07R6QU family 4 2
Vasopressin V2 receptor ligand AGN-PC-072QIH family 1 3
Cannabinoid receptor 1 ligand AGN-PC-07NHJ5 family 9 1
KiSS-1 receptor ligand SureCN5132924 family 2 4
Coagulation factor X and Prothrombin inhibitor N,1-bis[(3-carb... 1 1
Poly [ADP-ribose] polymerase 1 inhibitor SureCN4998361 family 1 1
Translocator protein inhibitor N,N-dibutyl-2-(7-chloro-2-pheny... 3 1
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
Translocator protein inhibitor 2-(7-Chloro-5-methyl-4-oxo-3-ph... 1 0
Cannabinoid receptor 1 ligand AGN-PC-07R5TU family 11 0
Cannabinoid receptor 1 ligand AGN-PC-07NHI2 family 4 1
Poly [ADP-ribose] polymerase 1 inhibitor SureCN3553433 family 22 0
Cannabinoid receptor 1 ligand AGN-PC-07RA3R family 15 0
Cannabinoid receptor 1 ligand SureCN3822127 family 5 0
Cannabinoid receptor 1 ligand AGN-PC-07R6QS family 5 0
Serine/threonine-protein kinase pim-1 and Calcium/calmodulin-d... 1 0
Tyrosine-protein kinase inhibitor (4-chloro-1H-indol-2-yl)-[(3... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00327052 CHEMBL1210700 Bioactive AGN-PC-088VZV
CFAMM00327051 CHEMBL1210780 Bioactive AGN-PC-04YSUM
CFAMM00327044 CHEMBL1210775 Bioactive SureCN1260541
CFAMM00327050 CHEMBL1210781 Bioactive SureCN2332790
CFAMM00327043 CHEMBL1210776 Bioactive AGN-PC-04YSO1
CFAMM00327049 CHEMBL1210782 Bioactive SureCN2330228
CFAMM00327042 CHEMBL1210779 Bioactive AGN-PC-04YSO2

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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