CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17446
Family Name Glucocorticoid receptor ligand N-[2-[[[5-amino-1-(4-fluorophenyl)pyrazole-4-carbonyl]amino]methyl]-3,3,3-trifluoro-2-hydroxypropyl]-N-ethyl-1H-indole-5-carboxamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00442607 Functional Category Bioactive
Superfamily Glucocorticoid receptor and Glucagon receptor Binder Superfamily
Class Class 1185

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Vascular endothelial growth factor receptor 1 and Angiopoietin... 29 127
TGF-beta receptor type-1 Ligand LY2157299 Family 13 56
Adenosine receptor A1 and Adenosine receptor A2a Ligand OSIP-3... 4 31
Sphingosine 1-phosphate receptor 1 ligand SureCN3029336 family 4 8
Orexin receptor type 2 and Orexin receptor type 1 ligand [(7R)... 10 10
TGF-beta receptor type-1 ligand 6-[4-ethyl-2-(6-methylpyridin-... 9 11
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 10
Mitogen-activated protein kinase 14 inhibitor AGN-PC-09M6OU fa... 8 7
Mitogen-activated protein kinase 14 inhibitor AGN-PC-069K8I fa... 12 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 1
Glucocorticoid receptor ligand N-ethyl-2-fluoro-N-[3,3,3-trifl... 16 7
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor dihydro-benz... 1 4
Mitogen-activated protein kinase 14 inhibitor N-ethyl-5-methyl... 17 3
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 14 2
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 2 3
Hepatocyte growth factor receptor ligand 5-[[6-(1-methylpyrazo... 4 0
MAP kinase-activated protein kinase 2 inhibitor 4-fluoro-N-[4-... 25 1
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 10 0
DNA gyrase subunit B inhibitor 5-[2-(ethylcarbamoyl)-4-[3-(tri... 2 4
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 17 0
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-fluoro... 5 1
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 4-[4... 1 1
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2
Glucocorticoid receptor ligand 5-amino-N-[2-[(1-ethyl-3,4-dihy... 1 0
Glucocorticoid receptor ligand 5-amino-N-[(2R)-2-[[(2,6-dichlo... 6 5
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 0
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00442607 CHEMBL465919 Bioactive N-[2-[[[5-amino-1-(4-fluorophenyl)pyrazole-4-carbonyl]amino]methyl]-3,3,3-trifluoro-2-hydroxypropyl]-N-ethyl-1H-indole-5-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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