CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17449
Family Name Adenosine receptor A2b and Adenosine receptor A1 ligand [4-(2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenyl]methyl N-phenylcarbamate family
No. of Seeds 6 No. of Other Members 15
Family Centroid CFAMM00278925 Functional Category Bioactive with Natural Product
Superfamily Adenosine receptor A2b and Adenosine receptor A2a Binder Superfamily 3
Class Class 3172

Cousin Family NamesSeedsMembers
Reverse transcriptase Inhibitor Delavirdine Family 1 68
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Adenosine receptor A1 and Adenosine receptor A2a Ligand SB-298... 53 320
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Reverse transcriptase Inhibitor Atevirdine Family 4 55
C-C chemokine receptor type 5 ligand AC1LAJEM family 4 14
Cathepsin K and Cathepsin S inhibitor dipeptidyl nitrile, 16f ... 3 18
NS5B protein inhibitor AC1NQMYG family 6 12
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 7 11
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 6
Cellular tumor antigen p53 inhibitor CHEMBL1418224 family 1 62
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 52 12
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 5 2
Adenosine receptor A2b and Adenosine receptor A1 ligand MRS 17... 10 0
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 4 53
Platelet-activating factor receptor ligand SureCN7491834 family 28 15
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-09ODY0 ... 2 5
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-0A9RSG ... 6 5
D(2) dopamine receptor and Alpha-1B adrenergic receptor ligand... 3 4
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 7 12
Scavenger receptor class B member 1 ligand methyl 9-[3-(4,6-di... 2 10
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 8 4
Adenosine receptor A2b ligand 2-[5-(2,6-dioxo-1,3-dipropyl-7H-... 1 0
Serine/threonine-protein kinase TBK1 and Inhibitor of nuclear ... 2 8
Adenosine receptor A2b and Adenosine receptor A2a ligand N-(4-... 2 14
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 6 6
Glycogen synthase kinase-3 beta and Casein kinase I isoform ga... 3 0
Phospholipase D1 and Phospholipase D2 inhibitor SureCN10311349... 2 14
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 1 1
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 2 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 0
Histamine H3 receptor ligand AGN-PC-075YVW family 1 2
KiSS-1 receptor ligand N-[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-... 1 0
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 1 0
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 0
Thromboxane-A synthase inhibitor AGN-PC-00NE8C family 2 3
Cell division cycle 7-related protein kinase inhibitor Pyrrolo... 2 6
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL4... 6 2
Adenosine receptor A2b and Adenosine receptor A2a ligand SureC... 2 0
Adenosine receptor A2b and Adenosine receptor A2a ligand SureC... 1 0
Adenosine receptor A2b and Adenosine receptor A2a ligand SureC... 2 0
Vascular endothelial growth factor receptor 2 and Vascular end... 1 0
Mitogen-activated protein kinase 1 and Aurora kinase A inhibit... 16 3
Histamine H3 receptor ligand SureCN7961030 family 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27430 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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