CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1745
Family Name 5-hydroxytryptamine receptor 6 ligand N-(3,5-dichlorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide family
No. of Seeds 7 No. of Other Members 2
Family Centroid CFAMM00327060 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 6 Ligand SB-357134 Superfamily
Class Class 1633

Cousin Family NamesSeedsMembers
Tumor necrosis factor Inhibitor Tgaac-94 Family 6 107
5-hydroxytryptamine receptor 6 Ligand Sb 258585 Family 11 121
5-hydroxytryptamine receptor 6 Ligand SB-357134 Family 13 2
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Pyruvate kinase PKLR and Pyruvate kinase PKM inhibitor AGN-PC-... 1 1
Alpha-2A adrenergic receptor and 5-hydroxytryptamine receptor ... 7 10
5-hydroxytryptamine receptor 6 ligand 1-(4-methoxy-3-piperazin... 6 3
5-hydroxytryptamine receptor 6 ligand 8-chloro-2-(4-methoxy-3-... 4 1
5-hydroxytryptamine receptor 6 ligand 6-bromo-1-(4-methoxy-3-p... 2 0
5-hydroxytryptamine receptor 6 ligand AGN-PC-0BRZ7B family 9 2
Neuropeptide Y receptor type 5 ligand 2-(7-chloro-3-oxo-1,4-be... 3 3
Neuropeptide Y receptor type 5 ligand N-[[4-[2-[7-(trifluorome... 1 1
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 14
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 2 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 10 1
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 5 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 5 1
Growth hormone secretagogue receptor type 1 ligand SureCN48020... 3 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 4-met... 3 3
5-hydroxytryptamine receptor 6 ligand N-(3-bromo-2,5-dichlorop... 2 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 3 3
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00327059 CHEMBL1210710 Bioactive SB-399885
CFAMM00327056 CHEMBL154525 Bioactive N-(3,4-dichlorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
CFAMM00327067 CHEMBL157175 Bioactive 4-methoxy-3-piperazin-1-yl-N-(2,4,5-trichlorophenyl)benzenesulfonamide
CFAMM00327066 CHEMBL348870 Bioactive N-(3-chlorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
CFAMM00327062 CHEMBL154273 Bioactive N-(5-chloro-2-methoxyphenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide
CFAMM00327060 CHEMBL345110 Bioactive N-(3,5-dichlorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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