CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17450
Family Name Collagenase 3 inhibitor (2R)-2-[[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonylamino]-2-(1-methoxycarbonylpiperidin-4-yl)acetic acid family
No. of Seeds 34 No. of Other Members 1
Family Centroid CFAMM00442631 Functional Category Bioactive
Superfamily 72 kDa type IV collagenase and Collagenase 3 Binder Superfamily 3
Class Class 3248

Cousin Family NamesSeedsMembers
Glycoprotein IIb/IIIa receptor Ligand Tirofiban Family 4 173
Neutrophil collagenase and 72 kDa type IV collagenase inhibito... 3 45
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 8
Collagenase 3 and A disintegrin and metalloproteinase with thr... 10 19
Collagenase 3 and 72 kDa type IV collagenase inhibitor N-[(6R)... 1 1
72 kDa type IV collagenase and Neutrophil collagenase inhibito... 12 20
72 kDa type IV collagenase and Collagenase 3 inhibitor 2-[(3Z)... 4 3
72 kDa type IV collagenase and Collagenase 3 inhibitor SureCN7... 5 2
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 3 0
Collagenase 3 inhibitor (2R)-2-[[4-(4-methylphenyl)phenyl]sulf... 3 1
Collagenase 3 inhibitor (2R)-2-[1-[(2-methylpropan-2-yl)oxycar... 4 2
Collagenase 3 and Interstitial collagenase inhibitor (2R)-2-[[... 3 0
72 kDa type IV collagenase and Collagenase 3 inhibitor SureCN7... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00442633 CHEMBL492384 Bioactive (2R)-2-[1-(cyclohexanecarbonyl)piperidin-4-yl]-2-[[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonylamino]acetic acid
CFAMM00442647 CHEMBL466237 Bioactive (2R)-2-[[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonylamino]-2-[1-(oxan-4-yloxycarbonyl)piperidin-4-yl]acetic acid
CFAMM00442660 CHEMBL467262 Bioactive (2R)-2-[[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonylamino]-2-[1-(2-methylpropoxycarbonyl)piperidin-4-yl]acetic acid
CFAMM00442639 CHEMBL468095 Bioactive (2R)-2-(1-ethoxycarbonylpiperidin-4-yl)-2-[[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonylamino]acetic acid
CFAMM00442653 CHEMBL494824 Bioactive (2R)-2-[1-(benzenesulfonyl)piperidin-4-yl]-2-[[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonylamino]acetic acid
CFAMM00442632 CHEMBL493179 Bioactive (2R)-2-[1-(2,2-dimethylpropanoyl)piperidin-4-yl]-2-[[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonylamino]acetic acid
CFAMM00442646 CHEMBL512237 Bioactive (2R)-2-[1-(tert-butylcarbamoyl)piperidin-4-yl]-2-[[5-(4-methoxyphenyl)thiophen-2-yl]sulfonylamino]acetic acid
CFAMM00442659 CHEMBL512613 Bioactive (2R)-2-[[5-[4-(2-methoxyethoxy)phenyl]thiophen-2-yl]sulfonylamino]-2-(1-propan-2-yloxycarbonylpiperidin-4-yl)acetic acid
CFAMM00442652 CHEMBL469138 Bioactive (2R)-2-[[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonylamino]-2-(1-pentan-3-yloxycarbonylpiperidin-4-yl)acetic acid
CFAMM00442638 CHEMBL466024 Bioactive SureCN3258416
CFAMM00442631 CHEMBL513823 Bioactive (2R)-2-[[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonylamino]-2-(1-methoxycarbonylpiperidin-4-yl)acetic acid
CFAMM00442644 CHEMBL466249 Bioactive (2R)-2-[[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonylamino]-2-[1-(propan-2-ylcarbamoyl)piperidin-4-yl]acetic acid
CFAMM00442658 CHEMBL467482 Bioactive (2R)-2-[[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonylamino]-2-[1-(2-methylpropylsulfonyl)piperidin-4-yl]acetic acid
CFAMM00442637 CHEMBL512275 Bioactive (2R)-2-[[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonylamino]-2-(1-propoxycarbonylpiperidin-4-yl)acetic acid
CFAMM00442630 CHEMBL468739 Bioactive (2R)-2-[[5-(4-hydroxyphenyl)thiophen-2-yl]sulfonylamino]-2-(1-propan-2-yloxycarbonylpiperidin-4-yl)acetic acid
CFAMM00442643 CHEMBL493989 Bioactive (2R)-2-[[5-(4-methoxyphenyl)thiophen-2-yl]sulfonylamino]-2-[1-(4-methylphenyl)sulfonylpiperidin-4-yl]acetic acid
CFAMM00442657 CHEMBL512243 Bioactive (2R)-2-[[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonylamino]-2-(1-propan-2-ylsulfonylpiperidin-4-yl)acetic acid
CFAMM00442636 CHEMBL492383 Bioactive (2R)-2-[1-(3,3-dimethylbutanoyl)piperidin-4-yl]-2-[[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonylamino]acetic acid
CFAMM00442650 CHEMBL466445 Bioactive (2R)-2-[[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonylamino]-2-(1-propylsulfonylpiperidin-4-yl)acetic acid
CFAMM00442629 CHEMBL466208 Bioactive (2R)-2-(1-propan-2-yloxycarbonylpiperidin-4-yl)-2-[[5-(4-propan-2-yloxyphenyl)thiophen-2-yl]sulfonylamino]acetic acid
CFAMM00442642 CHEMBL466060 Bioactive (2R)-2-(1-propan-2-yloxycarbonylpiperidin-4-yl)-2-[[5-(4-propoxyphenyl)thiophen-2-yl]sulfonylamino]acetic acid
CFAMM00442656 CHEMBL513645 Bioactive (2R)-2-(1-butylsulfonylpiperidin-4-yl)-2-[[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonylamino]acetic acid
CFAMM00442635 CHEMBL513148 Bioactive (2R)-2-(1-propan-2-yloxycarbonylpiperidin-4-yl)-2-[[5-[4-(trifluoromethoxy)phenyl]thiophen-2-yl]sulfonylamino]acetic acid
CFAMM00442649 CHEMBL467687 Bioactive (2R)-2-(1-benzylsulfonylpiperidin-4-yl)-2-[[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonylamino]acetic acid
CFAMM00442628 CHEMBL468731 Bioactive (2R)-2-(1-cyclopentyloxycarbonylpiperidin-4-yl)-2-[[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonylamino]acetic acid
CFAMM00442641 CHEMBL513655 Bioactive (2R)-2-(1-benzylpiperidin-4-yl)-2-[[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonylamino]acetic acid
CFAMM00442655 CHEMBL511433 Bioactive (2R)-2-[1-(2,2-dimethylpropoxycarbonyl)piperidin-4-yl]-2-[[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonylamino]acetic acid
CFAMM00442634 CHEMBL493177 Bioactive (2R)-2-[1-(diethylcarbamoyl)piperidin-4-yl]-2-[[5-(4-methoxyphenyl)thiophen-2-yl]sulfonylamino]acetic acid
CFAMM00442648 CHEMBL494167 Bioactive (2R)-2-[[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonylamino]-2-[1-(oxane-4-carbonyl)piperidin-4-yl]acetic acid
CFAMM00442640 CHEMBL468096 Bioactive (2R)-2-(1-butoxycarbonylpiperidin-4-yl)-2-[[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonylamino]acetic acid
CFAMM00442654 CHEMBL466052 Bioactive (2R)-2-[[5-(4-methoxyphenyl)thiophen-2-yl]sulfonylamino]-2-[1-(propan-2-ylcarbamoyl)piperidin-4-yl]acetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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