CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17462
Family Name Muscarinic acetylcholine receptor M2 and Muscarinic acetylcholine receptor M3 ligand ethyl 4-[[(2S)-1-[[(3S)-1-(1,3-benzodioxol-5-ylmethyl)-1-methylpyrrolidin-1-ium-3-yl]amino]-3-(4-methoxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate;iodide family
No. of Seeds 10 No. of Other Members 1
Family Centroid CFAMM00306824 Functional Category Bioactive
Superfamily Genome polyprotein Inhibitor Azapeptide Derivative Superfamily
Class Class 954

Cousin Family NamesSeedsMembers
Endothelin-1 receptor Ligand Atrasentan Family 127 336
Urotensin-2 receptor Ligand JNJ-28318706 Family 4 227
Integrin beta-1 and Integrin alpha-4 inhibitor (3S)-3-(3,4-dim... 5 61
Rho-associated protein kinase 2 inhibitor N-(7-chloro-1-oxo-2H... 2 0
Endothelin B receptor and Endothelin-1 receptor ligand SureCN8... 6 4
C-C chemokine receptor type 3 ligand 1-(3-cyanophenyl)-3-[6-[[... 2 5
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 2 9
Acrosin and Trypsin-1 inhibitor (4-methylphenyl) 4-(diaminomet... 10 13
Potassium voltage-gated channel subfamily H member 2 and Melan... 2 12
Integrin beta-1 and Integrin alpha-4 inhibitor 4-[[1-[2-[4-[(2... 2 8
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-075FY0 f... 1 0
Melanin-concentrating hormone receptor 1 and Potassium voltage... 3 6
Integrin beta-3 and Integrin alpha-2 inhibitor 3-(4-methoxyphe... 4 6
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 4 22
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 12 13
Integrin alpha-4 inhibitor SureCN14558473 family 7 4
C-C chemokine receptor type 2 ligand 2-amino-N-[2-[[(3R)-1-[(3... 2 2
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 4 7
Integrin beta-3 and Integrin alpha-V inhibitor (3R)-3-(1,3-ben... 5 0
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 2 0
Coagulation factor VII and Prothrombin inhibitor AGN-PC-0752MU... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00442734 CHEMBL466271 Bioactive ethyl 4-[[(2S)-1-[[(3S)-1-(1,3-benzodioxol-5-ylmethyl)-1-methylpyrrolidin-1-ium-3-yl]amino]-3-(4-bromophenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate;iodide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

43278 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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