CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17485
Family Name Acyl-CoA desaturase 1 inhibitor AGN-PC-077KJY family
No. of Seeds 5 No. of Other Members 4
Family Centroid CFAMM00442831 Functional Category Bioactive
Superfamily Beta-lactamase and Acyl-CoA desaturase 1 Binder Superfamily
Class Class 1677

Cousin Family NamesSeedsMembers
Beta-1 adrenergic receptor Ligand Acebutolol Family 2 27
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
C-C chemokine receptor type 1 Ligand BX-471 Family 10 67
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-(3-morpholinop... 24 102
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04UEH3 family 3 16
C-C chemokine receptor type 3 ligand SureCN6705515 family 2 16
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 2
D(3) dopamine receptor and D(4) dopamine receptor ligand N-[4-... 6 16
Cathepsin L1 and Cathepsin S inhibitor arylaminoethyl amide, 5... 4 5
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 9 3
Receptor-type tyrosine-protein kinase FLT3 ligand (3Z)-5-chlor... 1 4
Bifunctional epoxide hydrolase 2 inhibitor SureCN3178516 family 3 1
Bifunctional epoxide hydrolase 2 inhibitor 3-[4-[[4-(trifluoro... 5 22
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 6 11
Bifunctional epoxide hydrolase 2 and RAF proto-oncogene serine... 4 10
Bifunctional epoxide hydrolase 2 inhibitor 8-(2,6-difluorobenz... 4 1
Acyl-CoA desaturase 1 inhibitor AGN-PC-077KFD family 1 1
Dihydrofolate reductase inhibitor 3-[[2-chloro-4-(4,6-diamino-... 1 1
Thioredoxin glutathione reductase and Microtubule-associated p... 1 2
Sodium channel protein type 1 subunit alpha and Sodium channel... 3 0
Glucagon receptor ligand 2-chloro-N-[[3-chloro-4-(4-chlorophen... 1 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00442836 CHEMBL469061 Bioactive AGN-PC-077KIY
CFAMM00442829 CHEMBL469169 Bioactive SCD inhibitor
CFAMM00442835 CHEMBL469062 Bioactive AGN-PC-077KIZ
CFAMM00442832 CHEMBL467180 Bioactive AGN-PC-077KJX
CFAMM00442831 CHEMBL467181 Bioactive AGN-PC-077KJY

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

43659 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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