CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1749
Family Name Prothrombin inhibitor (2S)-N-[(4-carbamimidoyl-1,3-thiazol-2-yl)methyl]-1-[(2R)-3,3-diphenyl-2-(sulfamoylamino)propanoyl]pyrrolidine-2-carboxamide family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00327126 Functional Category Bioactive
Superfamily Prothrombin and Cationic trypsin Binder Superfamily 3
Class Class 3121

Cousin Family NamesSeedsMembers
Prothrombin Inhibitor RWJ-50353 Family 11 95
Cathepsin B and Cathepsin K Inhibitor L-006235-1 Family 19 75
Tubulin beta chain Inhibitor DOLASTATIN-10 Family 4 93
Histone deacetylase 1 and Histone deacetylase 4 Inhibitor 7-me... 3 14
Coagulation factor X Inhibitor Phso2-gly-(me-gly)-arg-(2-thiaz... 32 62
Fatty-acid amide hydrolase 1 Inhibitor 7-phenyl-1-(thiazol-2-y... 4 5
Prothrombin inhibitor (3R,6R,8aS)-N-[5-(diaminomethylideneamin... 4 1
Prothrombin inhibitor (6S,8aS)-N-[5-(diaminomethylideneamino)-... 12 10
Protease and Capsid scaffolding protein inhibitor AC1LAC7K family 2 5
Prothrombin and Cationic trypsin inhibitor (2S)-1-[(2R)-2-amin... 1 0
Coagulation factor X and Prothrombin inhibitor (2S)-2-(benzyls... 4 4
Coagulation factor X and Prothrombin inhibitor 2-[(3S)-3-benzy... 7 0
Trypsin-1 and Prothrombin inhibitor (6S,8aS)-N-[(2S)-5-(diamin... 1 1
Prothrombin and Cationic trypsin inhibitor 2-ketobenzothiazole... 3 0
Prothrombin and Cationic trypsin inhibitor 2-ketobenzothiazole... 3 3
Prothrombin inhibitor methyl 2-[(2S)-5-(diaminomethylideneamin... 4 2
Suppressor of tumorigenicity 14 protein and Serine protease he... 6 0
Prothrombin and Trypsin-1 inhibitor (2S)-1-[(2R)-2-amino-3,3-d... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00327128 CHEMBL121150 Bioactive 2-[[(2R)-1-[(2S)-2-[(4-carbamimidoyl-1,3-thiazol-2-yl)methylcarbamoyl]pyrrolidin-1-yl]-1-oxo-3,3-diphenylpropan-2-yl]amino]acetic acid
CFAMM00327126 CHEMBL121694 Bioactive (2S)-N-[(4-carbamimidoyl-1,3-thiazol-2-yl)methyl]-1-[(2R)-3,3-diphenyl-2-(sulfamoylamino)propanoyl]pyrrolidine-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48694 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543