CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17508
Family Name Alpha-1A adrenergic receptor and Alpha-2A adrenergic receptor ligand 2-[2-[(6S)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl]phenyl]-1,3-thiazole family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00443002 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine receptor 2B Binder Superfamily
Class Class 392

Cousin Family NamesSeedsMembers
Vascular endothelial growth factor Inhibitor PTC299 Family 6 145
Cytochrome P450 26A1 Inhibitor Rambazole Family 7 77
Steroid 17-alpha-hydroxylase/17,20 lyase Inhibitor 1-(1-(4-thi... 3 36
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 4 22
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-chlo... 11 20
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
NADH-ubiquinone oxidoreductase chain 3 Inhibitor 6-thiophen-3-... 2 0
Potassium voltage-gated channel subfamily H member 2 and Neuro... 2 3
Adenosine receptor A1 and Adenosine receptor A2b ligand SureCN... 1 0
DNA-(apurinic or apyrimidinic site) lyase and Neuropeptide S r... 1 4
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 3 10
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 5 27
Fatty-acid amide hydrolase 1 inhibitor AGN-PC-0A9RCZ family 7 7
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 7 21
Adenosine receptor A2b and Adenosine receptor A3 ligand 3-[5-(... 4 2
Adenosine receptor A2a and Adenosine receptor A1 ligand AGN-PC... 2 7
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 3 6
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... 4 5
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 4 1
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 4
D(4) dopamine receptor and D(2) dopamine receptor ligand 3-(1-... 1 0
Prostaglandin G/H synthase 2 inhibitor AGN-PC-00FW8Y family 1 1
Cytochrome P450 11B1, mitochondrial and Cytochrome P450 11B2, ... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00443002 CHEMBL468710 Bioactive 2-[2-[(6S)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl]phenyl]-1,3-thiazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27298 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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