CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17512
Family Name Androgen receptor ligand 4-[(1R,5R)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]octan-8-yl]naphthalene-1-carbonitrile family
No. of Seeds 8 No. of Other Members 7
Family Centroid CFAMM00443018 Functional Category Bioactive
Superfamily Androgen receptor Binder Superfamily 6
Class Class 3346

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake inhibitor Dibenzazepine Imipramine Family 8 178
D(2) dopamine receptor Ligand Nomifensine Family 6 100
Progesterone receptor Ligand 2,2,4-trimethyl-6-phenyl-1,2-dihy... 5 82
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 67
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 8 32
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 42
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 18
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 0
Sigma non-opioid intracellular receptor 1 ligand 1-[4-[1-adama... 4 23
Histamine H3 receptor ligand SureCN3052824 family 4 14
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00443019 CHEMBL468938 Bioactive AGN-PC-00DVCM
CFAMM00443012 CHEMBL570413 Bioactive 4-[(1R,5R)-3-hydroxy-3-propan-2-yl-8-azabicyclo[3.2.1]octan-8-yl]naphthalene-1-carbonitrile
CFAMM00443018 CHEMBL568786 Bioactive 4-[(1R,5R)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]octan-8-yl]naphthalene-1-carbonitrile
CFAMM00443024 CHEMBL578199 Bioactive 4-[(1R,5R)-3-ethenyl-3-hydroxy-8-azabicyclo[3.2.1]octan-8-yl]naphthalene-1-carbonitrile
CFAMM00443010 CHEMBL570237 Bioactive 4-[(1S,5S)-8-azabicyclo[3.2.1]octan-8-yl]naphthalene-1-carbonitrile
CFAMM00443016 CHEMBL568814 Bioactive 4-[(1R,5R)-3-ethyl-3-hydroxy-8-azabicyclo[3.2.1]octan-8-yl]naphthalene-1-carbonitrile
CFAMM00443022 CHEMBL570463 Bioactive 4-[(1R,5R)-3-cyclopropyl-3-hydroxy-8-azabicyclo[3.2.1]octan-8-yl]naphthalene-1-carbonitrile
CFAMM00443014 CHEMBL577196 Bioactive 4-[(1R,5R)-3-hydroxy-8-azabicyclo[3.2.1]octan-8-yl]naphthalene-1-carbonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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