CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17543
Family Name RAF proto-oncogene serine/threonine-protein kinase inhibitor arylaminobenzimidazole, 18 family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00443222 Functional Category Bioactive
Superfamily RAF proto-oncogene serine/threonine-protein kinase and Glucagon receptor Binder Superfamily
Class Class 681

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase B-raf inhibitor diaryl urea an... 12 93
RAF proto-oncogene serine/threonine-protein kinase Inhibitor R... 7 148
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
Hepatocyte growth factor receptor and Receptor-type tyrosine-p... 12 26
Hepatocyte growth factor receptor ligand SureCN4492034 family 2 2
Vascular endothelial growth factor receptor 2 and Mast/stem ce... 8 8
Growth hormone secretagogue receptor type 1 ligand 2-methyl-6-... 2 0
Rho-associated protein kinase 1 inhibitor SureCN4007647 family 8 4
ALK tyrosine kinase receptor ligand 4-fluoro-N-[1-[4-(propan-2... 1 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 1
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 8
Vascular endothelial growth factor receptor 2 ligand 2-aminobe... 3 5
Angiopoietin-1 receptor and Vascular endothelial growth factor... 2 0
RAF proto-oncogene serine/threonine-protein kinase inhibitor a... 8 6


External ID

Functional Category

Molecule Name

CFAMM00443222 CHEMBL513600 Bioactive arylaminobenzimidazole, 18
CFAMM00443221 CHEMBL471415 Bioactive arylaminobenzimidazole, 16
CFAMM00443220 CHEMBL470358 Bioactive AGN-PC-03JIUN
CFAMM00443219 CHEMBL486137 Bioactive AGN-PC-03JIVE
CFAMM00443223 CHEMBL471625 Bioactive arylaminobenzimidazole, 17

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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