CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17550
Family Name Leukotriene A-4 hydrolase inhibitor SureCN3030546 family
No. of Seeds 9 No. of Other Members 1
Family Centroid CFAMM00443255 Functional Category Bioactive
Superfamily Beta-3 adrenergic receptor and Pol polyprotein Binder Superfamily
Class Class 630

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Oxaprozin Family 33 450
Pristinamycin family 2 2
Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Fatty-acid amide hydrolase 1 Inhibitor 1-(5-(pyridin-2-yl)oxaz... 10 142
Prostacyclin receptor and Prostaglandin E2 receptor EP3 subtyp... 4 17
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-[5-(4-hydroxyphe... 4 36
Peroxisome proliferator-activated receptor alpha Ligand BMS-68... 10 16
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 7
Peroxisome proliferator-activated receptor delta ligand SureCN... 8 19
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 4 20
Beta-secretase 1 inhibitor SureCN8284176 family 2 4
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 13 0
Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-... 4 15
Thromboxane-A synthase and Thromboxane A2 receptor ligand Sure... 5 37
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 0
Fatty-acid amide hydrolase 1 inhibitor methyl 6-[2-[3-(4-pheny... 8 5
Fatty-acid amide hydrolase 1 inhibitor [(2S)-6-phenoxy-1,2,3,4... 3 6
Integrin beta-1 and Integrin alpha-4 inhibitor 4-[[(2S,4S)-4-f... 4 7
Peroxisome proliferator-activated receptor gamma and Peroxisom... 4 1
Sphingosine 1-phosphate receptor 1 ligand 6-[2-[4-phenyl-3-(tr... 2 3
Sphingosine 1-phosphate receptor 1 ligand AGN-PC-00DWQL family 2 2
Potassium voltage-gated channel subfamily H member 2 and 5-hyd... 2 2
Beta-secretase 1 and Cytochrome P450 3A4 inhibitor N-[(2S,3R)-... 3 7
Peroxisome proliferator-activated receptor alpha and Peroxisom... 5 2
Peroxisome proliferator-activated receptor gamma and Peroxisom... 10 5
Collagenase 3 inhibitor AGN-PC-03HW1J family 4 0
Peroxisome proliferator-activated receptor gamma and Peroxisom... 3 0
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 1 5
C-C chemokine receptor type 3 and Cytochrome P450 2D6 ligand 1... 1 1
Peroxisome proliferator-activated receptor alpha and Peroxisom... 2 1
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 6 4
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-(2,6-... 3 15
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 11 3
Peroxisome proliferator-activated receptor gamma and Peroxisom... 7 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00443264 CHEMBL516603 Bioactive AGN-PC-078Z8Z
CFAMM00443257 CHEMBL481671 Bioactive 4-[[(1S,5R)-3-[4-[4-(1,3-oxazol-2-yl)phenoxy]anilino]-8-azabicyclo[3.2.1]octan-8-yl]methyl]benzoic acid
CFAMM00443263 CHEMBL481672 Bioactive 4-[2-[(1S,5R)-3-[4-[4-(1,3-oxazol-2-yl)phenoxy]anilino]-8-azabicyclo[3.2.1]octan-8-yl]ethyl]benzoic acid
CFAMM00443256 CHEMBL470755 Bioactive SureCN5314401
CFAMM00443262 CHEMBL479759 Bioactive 4-[[methyl-[4-[4-[4-(1,3-oxazol-2-yl)phenoxy]anilino]cyclohexyl]amino]methyl]benzoic acid
CFAMM00443255 CHEMBL479378 Bioactive SureCN3030546
CFAMM00443260 CHEMBL479360 Bioactive AGN-PC-078Z6Q
CFAMM00443259 CHEMBL479956 Bioactive 4-[[3-[4-[4-(1,3-oxazol-2-yl)phenoxy]anilino]pyrrolidin-1-yl]methyl]benzoic acid
CFAMM00443258 CHEMBL479568 Bioactive AGN-PC-078Z7Y

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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