CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17565
Family Name Integrin alpha-4 inhibitor (2S)-2-[(2-bromo-3-oxospiro[3.5]non-1-en-1-yl)amino]-3-[4-(2-tert-butylimidazo[4,5-b]pyridin-3-yl)phenyl]propanoic acid family
No. of Seeds 9 No. of Other Members 0
Family Centroid CFAMM00443329 Functional Category Bioactive
Superfamily Integrin alpha-4 Inhibitor CDP323 Superfamily
Class Class 898

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial inhibitor folic acid analog... 59 98
Integrin alpha-4 Inhibitor CDP323 Family 8 17
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 6 44
C-C chemokine receptor type 5 ligand SureCN13543564 family 10 3
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 11 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00443326 CHEMBL520105 Bioactive (2S)-2-[(2-methylsulfanyl-3-oxospiro[3.5]non-1-en-1-yl)amino]-3-[4-(2-pyridin-3-ylimidazo[4,5-b]pyridin-3-yl)phenyl]propanoic acid
CFAMM00443332 CHEMBL486444 Bioactive (2S)-2-[(2-bromo-3-oxospiro[3.5]non-1-en-1-yl)amino]-3-[4-(2-propan-2-ylimidazo[4,5-b]pyridin-3-yl)phenyl]propanoic acid
CFAMM00443325 CHEMBL471742 Bioactive (2S)-2-[(2-bromo-3-oxospiro[3.5]non-1-en-1-yl)amino]-3-[4-[2-(cyanomethyl)imidazo[4,5-b]pyridin-3-yl]phenyl]propanoic acid
CFAMM00443331 CHEMBL520885 Bioactive (2S)-2-[(2-bromo-3-oxospiro[3.5]non-1-en-1-yl)amino]-3-[4-[2-(cyclopropylmethyl)imidazo[4,5-b]pyridin-3-yl]phenyl]propanoic acid
CFAMM00443324 CHEMBL507508 Bioactive (2S)-2-[(3-oxo-2-propan-2-ylsulfanylspiro[3.5]non-1-en-1-yl)amino]-3-[4-(2-pyridin-3-ylimidazo[4,5-b]pyridin-3-yl)phenyl]propanoic acid
CFAMM00443330 CHEMBL479345 Bioactive (2S)-2-[(2-bromo-3-oxospiro[3.5]non-1-en-1-yl)amino]-3-[4-(2-morpholin-3-ylimidazo[4,5-b]pyridin-3-yl)phenyl]propanoic acid
CFAMM00443329 CHEMBL472305 Bioactive (2S)-2-[(2-bromo-3-oxospiro[3.5]non-1-en-1-yl)amino]-3-[4-(2-tert-butylimidazo[4,5-b]pyridin-3-yl)phenyl]propanoic acid
CFAMM00443328 CHEMBL487438 Bioactive (2S)-2-[(2-bromo-3-oxospiro[3.5]non-1-en-1-yl)amino]-3-[4-[2-[1-(trifluoromethyl)cyclopropyl]imidazo[4,5-b]pyridin-3-yl]phenyl]propanoic acid
CFAMM00443327 CHEMBL521102 Bioactive (2S)-2-[(2-chloro-3-oxospiro[3.5]non-1-en-1-yl)amino]-3-[4-(2-pyridin-3-ylimidazo[4,5-b]pyridin-3-yl)phenyl]propanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45057 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543