CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17567
Family Name Leukotriene A-4 hydrolase inhibitor 4-[[(1S,5R)-3-[4-(2-fluorophenoxy)anilino]-8-azabicyclo[3.2.1]octan-8-yl]methyl]benzoic acid family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00443347 Functional Category Bioactive
Superfamily Leukotriene A-4 hydrolase and Matrix metalloproteinase-9 Binder Superfamily
Class Class 3140

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Tranilast Family 5 125
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 5
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 11 9
Leukotriene A-4 hydrolase inhibitor AGN-PC-0A9QDC family 2 5
Cystic fibrosis transmembrane conductance regulator inhibitor ... 2 3
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Growth hormone secretagogue receptor type 1 ligand (2R)-N-(1-b... 11 4
Capsid scaffolding protein inhibitor AC1MHP1L family 3 6
Leukotriene A-4 hydrolase inhibitor SureCN5313952 family 4 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00443348 CHEMBL480347 Bioactive SureCN3039571
CFAMM00443347 CHEMBL471954 Bioactive 4-[[(1S,5R)-3-[4-(2-fluorophenoxy)anilino]-8-azabicyclo[3.2.1]octan-8-yl]methyl]benzoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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