CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17574
Family Name 5-hydroxytryptamine receptor 1A and Gonadotropin-releasing hormone receptor ligand 4-[3-[4-[2-(trifluoromethyl)-1H-benzimidazol-4-yl]piperazin-1-yl]propoxy]-1,3-dihydrobenzimidazole-2-thione family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00443417 Functional Category Bioactive
Superfamily Neuropeptide Y receptor type 1 and Glutamate receptor ionotropic, NMDA 1 Binder Superfamily
Class Class 1268

Cousin Family NamesSeedsMembers
Platelet-derived growth factor receptor Ligand CP-868596 Family 3 91
DNA Binder Bisbenzimide (hoechst 33258) Family 4 159
D(2) dopamine receptor and D(3) dopamine receptor Ligand [2-(1... 17 100
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 3 23
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 2 22
Neuropeptide Y receptor type 5 and Alpha-1A adrenergic recepto... 8 2
Survival motor neuron protein inhibitor CHEMBL1379159 family 1 10
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 10
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 14
Cellular tumor antigen p53 and Prelamin-A/C inhibitor CHEMBL14... 2 11
Neuropeptide Y receptor type 1 ligand 2-[(4-chlorophenoxy)meth... 5 13
Neuropeptide Y receptor type 1 ligand 1-[3-[1-(cyclohexylmethy... 15 9
Coagulation factor X and Cationic trypsin inhibitor AGN-PC-075... 26 7
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 3
Cathepsin K and Cathepsin L1 inhibitor CHEBI:43424 family 2 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 16 3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 0
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 5 8
Dual specificity protein kinase TTK inhibitor 6-N-cyclohexyl-2... 12 2
Glutamate receptor ionotropic, NMDA 2B ligand 2-[[4-(4-chlorop... 4 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 2
5-hydroxytryptamine receptor 1A ligand AGN-PC-04UH85 family 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00443417 CHEMBL488812 Bioactive 4-[3-[4-[2-(trifluoromethyl)-1H-benzimidazol-4-yl]piperazin-1-yl]propoxy]-1,3-dihydrobenzimidazole-2-thione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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