CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17581
Family Name Prostaglandin E2 receptor EP3 subtype ligand (E)-3-[4-(4-chloro-2-fluorophenoxy)-1-methylindol-3-yl]-N-(2,4,5-trifluorophenyl)sulfonylprop-2-enamide family
No. of Seeds 7 No. of Other Members 0
Family Centroid CFAMM00443449 Functional Category Bioactive
Superfamily Prostaglandin E2 receptor EP3 subtype Binder Superfamily 3
Class Class 1298

Cousin Family NamesSeedsMembers
Apricoxib family 8 77
Prostaglandin E2 receptor EP3 subtype ligand (E)-N-(3,4-difluo... 3 3
Prostaglandin E2 receptor EP3 subtype ligand (E)-3-(1-methyl-4... 14 12
Prostaglandin E2 receptor EP3 subtype ligand (E)-N-(3,5-dichlo... 2 9
Prostaglandin E2 receptor EP3 subtype ligand N-(benzenesulfony... 17 15


External ID

Functional Category

Molecule Name

CFAMM00443448 CHEMBL472754 Bioactive (E)-3-[4-(3-chloro-4-fluorophenoxy)-1-methylindol-3-yl]-N-(2,4,5-trifluorophenyl)sulfonylprop-2-enamide
CFAMM00443454 CHEMBL475152 Bioactive (E)-3-[4-(4-chloro-2-fluorophenoxy)-1-methylindol-3-yl]-N-(3,4-difluorophenyl)sulfonylprop-2-enamide
CFAMM00443453 CHEMBL475349 Bioactive (E)-3-[4-(2,4-dichlorophenoxy)-1-methylindol-3-yl]-N-(2,4,5-trifluorophenyl)sulfonylprop-2-enamide
CFAMM00443452 CHEMBL475348 Bioactive (E)-3-[4-(3,4-dichlorophenoxy)-1-methylindol-3-yl]-N-(2,4,5-trifluorophenyl)sulfonylprop-2-enamide
CFAMM00443451 CHEMBL474948 Bioactive (E)-3-[4-(4-chlorophenoxy)-1-methylindol-3-yl]-N-(2,4,5-trifluorophenyl)sulfonylprop-2-enamide
CFAMM00443450 CHEMBL521777 Bioactive (E)-3-[4-(4-chloro-3-fluorophenoxy)-1-methylindol-3-yl]-N-(2,4,5-trifluorophenyl)sulfonylprop-2-enamide
CFAMM00443449 CHEMBL490896 Bioactive (E)-3-[4-(4-chloro-2-fluorophenoxy)-1-methylindol-3-yl]-N-(2,4,5-trifluorophenyl)sulfonylprop-2-enamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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