CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17586
Family Name 72 kDa type IV collagenase and Aminopeptidase N inhibitor ly52 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00443472 Functional Category Bioactive
Superfamily Beta-lactamase and Microtubule-associated protein tau Binder Superfamily 9
Class Class 2449

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Multidrug resistance protein Inhibitor Tariquidar Family 3 60
Histamine H3 receptor Ligand GSK239512 Family 2 65
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 14 214
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 8 57
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Bifunctional epoxide hydrolase 2 Inhibitor N-benzyl-6-(3,3,3-t... 21 62
Neutrophil elastase inhibitor phenyl N-[(2S)-1-[(2S)-2-[[(3S)-... 2 0
Disintegrin and metalloproteinase domain-containing protein 17... 14 9
Glycogen synthase kinase-3 beta and Protein kinase C alpha typ... 2 30
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 8 32
Potassium voltage-gated channel subfamily H member 2 and Kappa... 5 33
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 3-(1,3-... 2 9
Histamine H3 receptor ligand 3-[4-[3-[(2R)-2-methylpyrrolidin-... 1 5
D(2) dopamine receptor and 5-hydroxytryptamine receptor 2A lig... 1 1
Mu-type opioid receptor ligand AGN-PC-075GBK family 4 4
D(3) dopamine receptor ligand AGN-PC-075Z0O family 2 3
Vascular endothelial growth factor receptor 2 and Vascular end... 2 52
Histamine H3 receptor ligand 2-[4-(1-methylpyrrole-2-carbonyl)... 3 4
Seprase and Prolyl endopeptidase inhibitor N-[2-[(2S)-2-cyanop... 1 3
Glutamate receptor ionotropic, NMDA 2B ligand SureCN5532501 fa... 1 0
Substance-P receptor ligand (4R)-N-[(2R)-1-[benzyl(methyl)amin... 1 4
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 3 7
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
Gamma-aminobutyric acid receptor subunit pi and Gamma-aminobut... 2 10
Platelet-activating factor receptor ligand AGN-PC-001U4L family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00443472 CHEMBL472915 Bioactive ly52

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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