CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17590
Family Name Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70 inhibitor 2-[2-(3,5-dimethylanilino)pyrimidin-4-yl]-N-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,3-thiazole-5-carboxamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00443490 Functional Category Bioactive
Superfamily Tyrosine-protein kinase SYK and Neuropeptide Y receptor type 5 Binder Superfamily
Class Class 1642

Cousin Family NamesSeedsMembers
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 7 21
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 15 8
Orexin receptor type 2 and Orexin receptor type 1 ligand (2-me... 3 1
Tyrosine-protein kinase ITK/TSK and Tyrosine-protein kinase Lc... 2 2
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 4 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00443490 CHEMBL473229 Bioactive 2-[2-(3,5-dimethylanilino)pyrimidin-4-yl]-N-[(2R)-1-hydroxypropan-2-yl]-4-methyl-1,3-thiazole-5-carboxamide
CFAMM00443493 CHEMBL512172 Bioactive 3emg

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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