CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17602
Family Name Protein kinase C zeta type and Cyclin-dependent kinase 2 inhibitor indazole-benzimidazole, 4 family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00392767 Functional Category Bioactive
Superfamily Prelamin-A/C and Cyclin-dependent kinase 2 Binder Superfamily
Class Class 3178

Cousin Family NamesSeedsMembers
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 7 5
Serine/threonine-protein kinase Chk2 and Serine/threonine-prot... 3 6
Tyrosine-protein kinase JAK2 inhibitor 5-(3-methoxyphenyl)-N-[... 2 11
Glycogen synthase kinase-3 beta and Dual specificity protein k... 4 5
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 1 6
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 0
Protein kinase C zeta type and Cyclin-dependent kinase 2 inhib... 2 13
Macrophage colony-stimulating factor 1 receptor and Ephrin typ... 1 0
Fibroblast growth factor receptor 1 and Vascular endothelial g... 5 0
Vascular endothelial growth factor receptor 1 and Fibroblast g... 3 7
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 0
Cyclin-dependent kinase 1 and Proto-oncogene tyrosine-protein ... 5 13
Cyclin-dependent kinase 1 inhibitor N-[[5-[(3Z)-3-[4-(methoxym... 3 7
Type-1 angiotensin II receptor ligand 2-ethyl-6-methoxy-N-[[4-... 2 0
Cyclin-dependent kinase 1 and Receptor tyrosine-protein kinase... 2 3
Rho-associated protein kinase 2 inhibitor SureCN1519463 family 5 1
Gonadotropin-releasing hormone receptor ligand 4-[[4-[2-(4-ter... 3 3
Histone-arginine methyltransferase CARM1 inhibitor AGN-PC-07CR... 4 0
Thymidylate synthase inhibitor AGN-PC-003VK9 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00443560 CHEMBL514197 Bioactive (4Z)-2-methoxy-4-[3-[4-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1,2-dihydroindazol-6-ylidene]cyclohexa-2,5-dien-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48692 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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