CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17605
Family Name Substance-P receptor ligand (3aR,4R,5S,7aS)-5-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-4-(4-fluorophenyl)-2-methyl-1,3,3a,4,5,6,7,7a-octahydroisoindole family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00443576 Functional Category Bioactive
Superfamily Substance-P receptor and C-C chemokine receptor type 2 Binder Superfamily
Class Class 100

Cousin Family NamesSeedsMembers
Opioid receptor ligand synthetic opioid methadone analog Dextr... 2 108
Serotonin re-uptake Inhibitor Citalopram Family 6 4
Dopamine reuptake and Noradrenergic re-uptake Inhibitor Cocain... 13 136
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Nicotinic acetylcholine receptor Ligand Benztropine Mesylate F... 10 20
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
Sodium-dependent dopamine transporter and Muscarinic acetylcho... 2 1
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 2 11
Sodium-dependent serotonin transporter and Transporter inhibit... 1 0
Sodium-dependent serotonin transporter and Sodium-dependent do... 3 1
Muscarinic acetylcholine receptor M3 ligand 3-[8-methyl-8-(2-p... 3 0
Substance-P receptor ligand 1-[[(1R,2R,3S)-3-[[3,5-bis(trifluo... 4 3
Substance-P receptor ligand AGN-PC-03NGZP family 3 0
Substance-P receptor ligand (1R,2S,3S)-3-[(1R)-1-[3,5-bis(trif... 8 0
Substance-P receptor ligand 1-[(3S,4R)-3-[(1R)-1-[3,5-bis(trif... 9 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00443575 CHEMBL490869 Bioactive (3aR,4R,5S,7aS)-5-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-4-(4-fluorophenyl)-N-methyl-1,3,3a,4,5,6,7,7a-octahydroisoindole-2-carboxamide
CFAMM00443574 CHEMBL484134 Bioactive 1-[(3aR,4R,5S,7aS)-5-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-4-(4-fluorophenyl)-1,3,3a,4,5,6,7,7a-octahydroisoindol-2-yl]ethanone
CFAMM00443573 CHEMBL473680 Bioactive (3aR,4R,5S,7aS)-5-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-4-(4-fluorophenyl)-2,3,3a,4,5,6,7,7a-octahydro-1H-isoindole
CFAMM00443576 CHEMBL484133 Bioactive (3aR,4R,5S,7aS)-5-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-4-(4-fluorophenyl)-2-methyl-1,3,3a,4,5,6,7,7a-octahydroisoindole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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