CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17607
Family Name Beta-3 adrenergic receptor ligand SureCN5704018 family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00443577 Functional Category Bioactive
Superfamily Caspase-1 and Cytochrome P450 3A4 Binder Superfamily
Class Class 137

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Dolasetron Family 12 171
Sodium channel protein type 5 subunit alpha Ligand Disopyramid... 4 352
Prostaglandin G/H synthase 2 Inhibitor Niflumic Acid Family 7 119
Histamine H1 receptor Ligand (s)-(+)-dimethindene Maleate Family 6 12
Histone deacetylase 1 Inhibitor MS-275 Family 4 41
Dihydroorotate dehydrogenase Inhibitor Brequinar Family 9 122
Retinoic acid receptor alpha Ligand LG100268 Family 2 33
Coagulation factor X Inhibitor Otamixaban Family 9 21
Dihydroorotate dehydrogenase Inhibitor Cinchoninic Acid Family 1 21
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Transient receptor potential cation channel subfamily V member... 6 23
RAF proto-oncogene serine/threonine-protein kinase Inhibitor 5... 3 7
Egl nine homolog 2 Inhibitor Pyridine-2,4-dicarboxylic Acid Fa... 2 21
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 24 64
Renin Inhibitor CP-305202 Family 9 30
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Isoqui... 1 6
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 3 27
Coagulation factor X inhibitor (2S)-(3'-AMIDINO-3-BIPHENYL)-5-... 1 0
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 2 22
Prostaglandin E2 receptor EP4 subtype and Prostaglandin D2 rec... 8 17
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 3 28
Sodium-dependent serotonin transporter and D(2) dopamine recep... 13 2
Retinoic acid receptor alpha and Retinoic acid receptor beta l... 1 2
Cannabinoid receptor 2 ligand [(4R,4aS,8aR)-4-hydroxy-4-phenyl... 2 41
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 6 4
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 4
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 4 7
Dipeptidyl peptidase 4 inhibitor AGN-PC-09QM95 family 1 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor AG... 1 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand [(4S,... 5 2
B1 bradykinin receptor ligand AGN-PC-00CTAF family 1 3
Egl nine homolog 1 inhibitor 2-[5-methyl-6-[[1-oxo-2-(4-phenyl... 4 3
B1 bradykinin receptor ligand methyl 2-fluoro-6-[3-fluoro-4-[[... 22 11
B1 bradykinin receptor ligand methyl 2-[4-[(1R)-1-[[3-[(2-cyan... 8 7
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 7 0
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 2 1
Hydroxycarboxylic acid receptor 2 and Cytochrome P450 2C9 liga... 2 6
Coagulation factor VII inhibitor 2-[2-[(1-aminoisoquinolin-6-y... 1 14
Rho-associated protein kinase 2 inhibitor 2-hydroxyethyl 3-[2-... 2 0
Coagulation factor X and Tissue factor inhibitor AGN-PC-02WN8Y... 7 22
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 4 2
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 1
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 5
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 2 1
Beta-3 adrenergic receptor ligand N-[4-[2-[[(2R)-2-hydroxy-2-p... 4 10
Serine/threonine-protein kinase Sgk1 inhibitor SureCN3774571 f... 2 18
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 1 1
Retinoic acid receptor alpha and Retinoic acid receptor beta l... 1 0
ATP-sensitive inward rectifier potassium channel 11 ligand N-[... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00443577 CHEMBL521406 Bioactive SureCN5704018

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

23197 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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