CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17609
Family Name Adenosine receptor A1 and Adenosine receptor A3 ligand CHEMBL473839 family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00406676 Functional Category Bioactive
Superfamily Adenosine receptor A1 and Adenosine receptor A3 Binder Superfamily 11
Class Class 3418

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
Reverse transcriptase Inhibitor Nevirapine Family 23 640
Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 25 124
Cyclin-dependent kinase 4 Inhibitor PD-332991 Family 13 155
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
XL-888 family 16 85
Class II cytokine receptor Ligand IL-10 Family 7 45
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 4 6
Calcitonin gene-related peptide type 1 receptor Ligand Isomer ... 30 31
Proto-oncogene tyrosine-protein kinase Src Inhibitor 5,7-diphe... 2 11
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Metabotropic glutamate receptor 5 Ligand 3-cyano-5-fluoro-n-(p... 2 9
RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... 20 90
Prothrombin inhibitor 2-[(2S)-1-[(2R)-2-amino-3-phenylpropanoy... 3 16
Tyrosine-protein kinase Lck and Tyrosine-protein kinase HCK in... 8 7
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 34 11
Platelet-activating factor receptor ligand SureCN9384429 family 11 3
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 6 1
Serine/threonine-protein kinase D1 and Polycystin-2 inhibitor ... 3 7
Histamine H3 receptor ligand 1-[1-[1-[(2-aminopyridin-4-yl)met... 16 9
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
5-hydroxytryptamine receptor 1A ligand AGN-PC-03ZB72 family 10 8
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QM1E family 8 15
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07CBUP family 2 3
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 13 3
Fatty-acid amide hydrolase 1 inhibitor [5-(4-chlorophenyl)tria... 2 2
Tyrosine-protein kinase JAK2 and Focal adhesion kinase 1 inhib... 11 3
Prothrombin inhibitor 2-[3-cyano-6-(2,2-difluoro-2-pyridin-2-y... 3 0
Aurora kinase B and Aurora kinase A inhibitor 4-amino-N-[3-[[(... 5 3
Vascular endothelial growth factor receptor 2 ligand (3Z)-3-[5... 4 11
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 8 5
Melanin-concentrating hormone receptor 1 ligand 6-(4-chlorophe... 8 1
Renin inhibitor AGN-PC-073MLF family 7 6
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 1
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Corticoster... 2 0
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
Orexin receptor type 2 and Orexin receptor type 1 ligand SureC... 2 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 7 2
Adenosine receptor A1 and Adenosine receptor A3 ligand AGN-PC-... 3 6
Poly [ADP-ribose] polymerase 1 inhibitor Piperazine analogue, ... 4 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN8... 3 0
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 12 6
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 1 2
Histamine H3 receptor ligand 6-[4-[2-[(2R)-2-methylpyrrolidin-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00443580 CHEMBL502005 Bioactive AGN-PC-077Q1T

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

42616 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543