CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17629
Family Name Nitric oxide synthase, brain and Nitric oxide synthase, inducible inhibitor N-{(3s,4s)-4-[(6-Amino-4-Methylpyridin-2-Yl)methyl]pyrrolidin-3-Yl}-N'-(4-Chlorobenzyl)ethane-1,2-Diamine family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00331999 Functional Category Bioactive
Superfamily Reverse transcriptase and Amine oxidase [flavin-containing] A Binder Superfamily
Class Class 2257

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Pyrimethamine Family 10 145
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Epidermal growth factor receptor Ligand N4-(3-chlorophenyl)qui... 7 39
Adenosine receptor A1 and Adenosine receptor A2a Ligand 3-benz... 1 6
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 9 24
Oestrogen receptor Ligand 4-benzyl-2,6-diisobutylamino-pyrimid... 5 37
Histamine H4 receptor Ligand A-943931 Family 14 11
Macrophage migration inhibitory factor Inhibitor 1-(2-chloroph... 2 22
Sodium-dependent serotonin transporter Inhibitor 6-chloro-2-pi... 5 35
Adenosine kinase inhibitor 5-(4-chlorophenyl)-6-[2-(6-morpholi... 8 8
Bloom syndrome protein inhibitor SR 57227A family 2 12
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and Thyrotropi... 1 2
Histamine H4 receptor ligand 4-[(3R)-3-(methylamino)pyrrolidin... 7 6
Corticotropin-releasing factor receptor 1 ligand 5-(2,4-dichlo... 5 17
Sodium-dependent serotonin transporter and Sodium-dependent no... 5 3
Dipeptidyl peptidase 4 inhibitor Aminomethylpyrimidine 1ck family 6 3
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 10
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 1
Growth hormone secretagogue receptor type 1 ligand AGN-PC-0760... 4 0
Cannabinoid receptor 2 ligand 8-(2-chlorophenyl)-9-cyclopropyl... 4 5
Adenosine kinase inhibitor 4-[2-[5-(4-chlorophenyl)-6-piperazi... 3 1
Nitric oxide synthase, inducible inhibitor SureCN2258300 family 2 24
Dihydrofolate reductase inhibitor 5-[4-[(3,4-dichlorophenyl)me... 1 0
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 1 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 7 0
Nitric oxide synthase, brain and Nitric oxide synthase, endoth... 1 0
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 2
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand 4-N-[... 16 21


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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