CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17650
Family Name Cholecystokinin receptor type A ligand AGN-PC-077KXF family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00443719 Functional Category Bioactive
Superfamily Cholecystokinin receptor type A and Prelamin-A/C Binder Superfamily
Class Class 227

Cousin Family NamesSeedsMembers
Adenosine receptor A2a Ligand KW-6002 Family 18 195
Platelet-derived growth factor receptor Ligand CP-868596 Family 3 91
AP26113 family 16 90
RAF proto-oncogene serine/threonine-protein kinase Inhibitor R... 7 148
DNA Binder Bisbenzimide (hoechst 33258) Family 4 159
Peptide deformylase, mitochondrial Inhibitor Epiroprim Family 5 68
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(3'-methoxyphenyl) ... 9 93
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 9 Inhibi... 10 35
D(2) dopamine receptor and D(3) dopamine receptor Ligand [2-(1... 17 100
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
Adenosine receptor A1 and Adenosine receptor A2a Ligand SB-298... 53 320
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Divapl... 3 47
Reverse transcriptase Inhibitor UK-129485 Family 23 221
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 4
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 6 35
Adenosine receptor A1 and Adenosine receptor A2b ligand 3-meth... 7 19
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-[4-[... 12 15
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 39 10
Glucocorticoid receptor ligand (2R)-1,1,1-trifluoro-4-(2-metho... 2 5
Adenosine receptor A2b and Adenosine receptor A1 ligand SureCN... 52 12
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 3
Adenosine receptor A2b and Adenosine receptor A1 ligand MRS 17... 10 0
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 5 4
Thyroid hormone receptor beta and Cruzipain ligand CHEMBL14730... 1 12
Cellular tumor antigen p53 and Lysosomal alpha-glucosidase inh... 1 6
Histamine H3 receptor ligand SureCN7251693 family 3 1
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 2 4
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 2
Coagulation factor X and Cationic trypsin inhibitor AGN-PC-075... 26 7
Platelet-activating factor receptor ligand SureCN7497229 family 4 2
Cannabinoid receptor 1 ligand AGN-PC-03I5TW family 3 12
Melanin-concentrating hormone receptor 1 ligand SureCN3334861 ... 1 3
Cholecystokinin receptor type A ligand AGN-PC-0A9ULH family 8 8
Adenosine receptor A1 and Adenosine receptor A3 ligand SureCN5... 3 1
Insulin receptor and Insulin-like growth factor 1 receptor lig... 17 7
Dual specificity protein kinase TTK inhibitor 6-N-cyclohexyl-2... 3 1
5-hydroxytryptamine receptor 2A and Sodium-dependent serotonin... 3 14
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 7
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 5 1
Histamine H1 receptor and Histamine H4 receptor ligand 1H-benz... 2 7
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 6 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 10 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 0
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 5 7
Adenosine receptor A2b ligand 2-[5-(2,6-dioxo-1,3-dipropyl-7H-... 1 0
Serine/threonine-protein kinase TBK1 and Inhibitor of nuclear ... 2 8
Epidermal growth factor receptor ligand N-[3-[7-[2-methoxy-4-(... 9 3
Dual specificity protein kinase TTK inhibitor 2-[1-[4-[[6-(cyc... 8 0
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 7 3
Smoothened homolog and Mitogen-activated protein kinase 14 inh... 7 11
Platelet-derived growth factor receptor alpha and Vascular end... 3 1
Activated CDC42 kinase 1 inhibitor 5-(2-fluorophenyl)-N-[[(2S)... 5 0
Growth hormone secretagogue receptor type 1 ligand SureCN36800... 14 42
Growth hormone secretagogue receptor type 1 ligand SureCN36380... 6 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 1 0
Rho-associated protein kinase 1 inhibitor SureCN4007647 family 8 4
Glycogen synthase kinase-3 beta and Casein kinase I isoform ga... 3 0
Aromatase inhibitor 2-(imidazol-1-ylmethyl)-6-methoxy-1-phenyl... 2 8
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 1 0
Histone-arginine methyltransferase CARM1 inhibitor AGN-PC-00HE... 4 4
Growth hormone secretagogue receptor type 1 ligand N-[(1R)-2-(... 3 2
Orexin receptor type 2 and Orexin receptor type 1 ligand 9-(4,... 2 5
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 8-[(6,7... 6 8
Collagenase 3 inhibitor 5-[4-[4-(1H-benzimidazol-2-yl)phenoxy]... 3 0
Collagenase 3 inhibitor 1-[6-[4-(1H-benzimidazol-2-yl)phenoxy]... 3 0
Tyrosine-protein kinase Lck and Proto-oncogene tyrosine-protei... 4 3
Adenosine receptor A1 and Adenosine receptor A2b ligand (2,5-d... 2 0
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 1
Adenosine receptor A2b and Adenosine receptor A1 ligand N-(3,4... 1 8
RAF proto-oncogene serine/threonine-protein kinase inhibitor a... 8 6
Cyclin-dependent kinase 1 and Receptor tyrosine-protein kinase... 2 3
Insulin-like growth factor 1 receptor ligand SureCN311483 family 3 0
Gastrin/cholecystokinin type B receptor ligand AGN-PC-077L8M f... 24 10
Cholecystokinin receptor type A ligand AGN-PC-077L8J family 22 2
Translocator protein inhibitor AGN-PC-04X3HY family 10 1
Tyrosine-protein kinase SYK and Lysine--tRNA ligase inhibitor ... 8 8
Cholecystokinin receptor type A ligand SureCN3132309 family 11 0
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 3 8
Adenosine receptor A2b and Adenosine receptor A2a ligand 1-eth... 5 2
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 3 5
Adenosine receptor A1 and Adenosine receptor A2b ligand N-[2-[... 2 1
LIM domain kinase 2 and LIM domain kinase 1 inhibitor SureCN36... 1 1
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 1 1
Vascular endothelial growth factor receptor 2 and Vascular end... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00443719 CHEMBL476095 Bioactive AGN-PC-077KXF
CFAMM00443718 CHEMBL477996 Bioactive AGN-PC-077KZ7

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543