CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17656
Family Name Cannabinoid receptor 1 ligand 1-[4-[3-cyclopropyl-5-(trifluoromethyl)phenyl]sulfonylpiperazin-1-yl]-2-[4-(trifluoromethyl)phenyl]ethanone family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00443798 Functional Category Bioactive
Superfamily Cannabinoid receptor 1 and Potassium voltage-gated channel subfamily H member 2 Binder Superfamily 2
Class Class 5225

Cousin Family NamesSeedsMembers
Bavisant family 9 65
Carbonic anhydrase 2 Inhibitor N-benzyl-4-sulfamoyl-benzamide ... 12 44
Muscarinic acetylcholine receptor M2 ligand [4-[(3R)-3-methyl-... 3 4
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 4
Cannabinoid receptor 2 ligand AGN-PC-04VLWN family 9 4
Cannabinoid receptor 2 ligand N-cyclohexyl-4-propan-2-yl-3-pyr... 2 2
Cannabinoid receptor 1 and Potassium voltage-gated channel sub... 4 0


External ID

Functional Category

Molecule Name

CFAMM00443801 CHEMBL489438 Bioactive [4-[3-cyclopropyl-5-(trifluoromethyl)phenyl]sulfonylpiperazin-1-yl]-[(1R,2R)-2-[4-(trifluoromethyl)phenyl]cyclopropyl]methanone
CFAMM00443799 CHEMBL522114 Bioactive [4-[3-cyclopropyl-5-(trifluoromethyl)phenyl]sulfonylpiperazin-1-yl]-[4-(trifluoromethyl)phenyl]methanone
CFAMM00443798 CHEMBL516900 Bioactive 1-[4-[3-cyclopropyl-5-(trifluoromethyl)phenyl]sulfonylpiperazin-1-yl]-2-[4-(trifluoromethyl)phenyl]ethanone
CFAMM00443797 CHEMBL476253 Bioactive AGN-PC-0694UI

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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