CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17669
Family Name 5-hydroxytryptamine receptor 1A ligand AGN-PC-04UH85 family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00443863 Functional Category Bioactive
Superfamily Cellular tumor antigen p53 and Acyl-CoA:cholesterol acyltransferase Binder Superfamily
Class Class 875

Cousin Family NamesSeedsMembers
Potassium-transporting ATPase alpha chain 1 Inhibitor Rabepraz... 4 113
Potassium-transporting ATPase alpha chain 1 Inhibitor Pantopra... 1 3
Platelet-derived growth factor receptor Ligand CP-868596 Family 3 91
DNA Binder Bisbenzimide (hoechst 33258) Family 4 159
D(2) dopamine receptor and D(3) dopamine receptor Ligand [2-(1... 17 100
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 3 23
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-[3-(4-... 7 128
Fatty-acid amide hydrolase 1 Inhibitor BMS-1 Family 5 22
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 10 46
Neuropeptide Y receptor type 5 and Alpha-1A adrenergic recepto... 8 2
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 3
Survival motor neuron protein inhibitor CHEMBL1379159 family 1 10
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 14
Cellular tumor antigen p53 and Prelamin-A/C inhibitor CHEMBL14... 2 11
Neuropeptide Y receptor type 1 ligand 2-[(4-chlorophenoxy)meth... 5 13
Neuropeptide Y receptor type 1 ligand 1-[3-[1-(cyclohexylmethy... 15 9
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 3
Dual specificity protein kinase TTK inhibitor 6-N-cyclohexyl-2... 12 2
Prostaglandin D2 receptor 2 ligand 2-[2-[(5-acetyl-2-methoxyph... 11 16
Glutamate receptor ionotropic, NMDA 2B ligand 2-[[4-(4-chlorop... 4 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 2
Orexin receptor type 2 and Orexin receptor type 1 ligand (2S)-... 1 0
Leukotriene A-4 hydrolase inhibitor AGN-PC-00EW8S family 1 2
Cyclin-dependent kinase 1 inhibitor AGN-PC-075VQQ family 2 0
D(2) dopamine receptor ligand 4-bromo-6-[2-[4-(2-methoxyphenyl... 2 3
5-hydroxytryptamine receptor 1A and Gonadotropin-releasing hor... 3 0
Metabotropic glutamate receptor 2 ligand 2-[[(1R,5S)-6-[(2,5-d... 2 3
Nociceptin receptor and Delta-type opioid receptor ligand 2-[3... 2 1
Histone-arginine methyltransferase CARM1 inhibitor AGN-PC-07CR... 4 0
Cytochrome P450 2C19 and Cytochrome P450 1A2 inhibitor 2-hepty... 4 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00443863 CHEMBL477199 Bioactive AGN-PC-04UH85
CFAMM00443858 CHEMBL479231 Bioactive AGN-PC-04UHG8

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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