CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1767
Family Name Plasmepsin-2 inhibitor N-[(2S)-1-[[(2S)-6-amino-1-[4-[(6-methoxyquinolin-8-yl)amino]pentylamino]-1-oxohexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-[4-[[(2S,3S)-1-[[(3S,4S)-1-(butylamino)-3-hydroxy-6-methyl-1-oxoheptan-4-yl]amino]-3-methyl-1-oxopentan-2-yl]carbamoyl]phenoxy]benzamide family
No. of Seeds 5 No. of Other Members 12
Family Centroid CFAMM00327207 Functional Category Bioactive
Superfamily Plasmepsin-2 and Cathepsin D Binder Superfamily
Class Class 630

Cousin Family NamesSeedsMembers
DNA Binder Primaquine Family 3 245
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(4-methoxyphenyl)qu... 2 11
Acetylcholinesterase and Muscarinic acetylcholine receptor M2 ... 2 7
Somatostatin receptor type 5 and Somatostatin receptor type 1 ... 2 8
Vascular endothelial growth factor receptor 2 and Aurora kinas... 3 3
B2 bradykinin receptor ligand SureCN7749611 family 4 1
B2 bradykinin receptor ligand (E)-3-[6-(2-oxopyrrolidin-1-yl)p... 3 2
B2 bradykinin receptor ligand SureCN8516699 family 3 2
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 12 0
Plasmepsin-2 and Cathepsin D inhibitor 4-[4-[[(2S,3S)-1-[[(3S,... 3 0
Serine/threonine-protein kinase Chk1 inhibitor SureCN4854955 f... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00327216 CHEMBL1790774 Bioactive N-[(2R)-1-[[(2R)-6-amino-1-[4-[(6-methoxyquinolin-8-yl)amino]pentylamino]-1-oxohexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-[4-[[(2S,3R)-1-[[(3S,4S)-1-(butylamino)-3-hydroxy-6-methyl-1-oxoheptan-4-yl]amino]-3-methyl-1-oxopentan-2-yl]carbamoyl]phenoxy]benzamide
CFAMM00327221 CHEMBL1790772 Bioactive [4-[[(2R)-1-[[(2R)-6-amino-1-[4-[(6-methoxyquinolin-8-yl)amino]pentylamino]-1-oxohexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-oxobutyl] 6-[[(2S,3R)-1-[[(3S,4S)-1-(butylamino)-3-hydroxy-6-methyl-1-oxoheptan-4-yl]amino]-3-methyl-1-oxopentan-2-yl]carbamoyl]naphthalene-2-carboxylate
CFAMM00327207 CHEMBL1213687 Bioactive N-[(2S)-1-[[(2S)-6-amino-1-[4-[(6-methoxyquinolin-8-yl)amino]pentylamino]-1-oxohexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-[4-[[(2S,3S)-1-[[(3S,4S)-1-(butylamino)-3-hydroxy-6-methyl-1-oxoheptan-4-yl]amino]-3-methyl-1-oxopentan-2-yl]carbamoyl]phenoxy]benzamide
CFAMM00327220 CHEMBL1790773 Bioactive 6-N-[(2R)-1-[[(2R)-6-amino-1-[4-[(6-methoxyquinolin-8-yl)amino]pentylamino]-1-oxohexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-N-[(2S,3R)-1-[[(3S,4S)-1-(butylamino)-3-hydroxy-6-methyl-1-oxoheptan-4-yl]amino]-3-methyl-1-oxopentan-2-yl]naphthalene-2,6-dicarboxamide
CFAMM00327212 CHEMBL216917 Bioactive 4-[4-[[(2S)-1-[[(3S,4S)-1-(butylamino)-3-hydroxy-6-methyl-1-oxoheptan-4-yl]amino]-3-methyl-1-oxopentan-2-yl]carbamoyl]phenoxy]-N-[(2S)-1-[[(2S)-1-[4-[(6-methoxyquinolin-8-yl)amino]pentylamino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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