CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17677
Family Name Alpha-2C adrenergic receptor and Alpha-2B adrenergic receptor ligand AGN-PC-077LK0 family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00192554 Functional Category Bioactive
Superfamily Alpha-2C adrenergic receptor and Alpha-2B adrenergic receptor Binder Superfamily 8
Class Class 2449

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase Chk1 and Serine/threonine-prot... 23 121
Serine/threonine-protein kinase PLK1 Inhibitor Bi 6727 Family 15 81
Gamma-secretase subunit APH-1B Inhibitor E2012 Family 3 67
Glucokinase Inhibitor GKA1 Family 2 67
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
Bifunctional epoxide hydrolase 2 Inhibitor N-benzyl-6-(3,3,3-t... 21 62
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 2 3
Metabotropic glutamate receptor 5 Ligand 3-methoxy-n-(6-methyl... 3 15
Reverse transcriptase/RNaseH inhibitor AC1LALKM family 2 19
Hepatocyte growth factor receptor and Receptor-type tyrosine-p... 12 26
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 3
Muscarinic acetylcholine receptor M2 and Muscarinic receptor 3... 4 3
Somatostatin receptor type 5 ligand AGN-PC-080TDB family 10 14
Somatostatin receptor type 5 ligand AGN-PC-088VSK family 2 3
Bifunctional epoxide hydrolase 2 inhibitor SureCN3216677 family 4 9
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 15
Calcium/calmodulin-dependent protein kinase kinase 2 and Focal... 3 17
Reverse transcriptase/RNaseH and Cytochrome P450 2C19 inhibito... 7 2
Ceramide glucosyltransferase and Cytochrome P450 3A4 inhibitor... 10 15
C-C chemokine receptor type 5 ligand N-[(3R)-3-[4-[4-methoxy-N... 13 1
MAP kinase-activated protein kinase 2 inhibitor N-[4-(4-oxospi... 3 0
Growth hormone secretagogue receptor type 1 and Potassium volt... 3 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 8 4
Rho-associated protein kinase 1 and cAMP-dependent protein kin... 1 11
Beta-1 adrenergic receptor ligand N-[2-[[(2S)-3-(2-cyanophenox... 2 1
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 6
Motilin receptor ligand SureCN2765637 family 1 1
Focal adhesion kinase 1 inhibitor 2-[[2-(2-methoxy-4-morpholin... 2 1
Mast/stem cell growth factor receptor Kit and Serine/threonine... 11 29
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 2
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 4 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 6 0
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 6
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 2
Adenosine kinase inhibitor AGN-PC-0757MS family 2 0
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 1 0
Alpha-2C adrenergic receptor and Alpha-2B adrenergic receptor ... 1 2
Alpha-2C adrenergic receptor and Alpha-2B adrenergic receptor ... 6 1
Histamine H3 receptor ligand AGN-PC-03Z8HB family 3 0
C-C chemokine receptor type 8 and Potassium voltage-gated chan... 1 3
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 1 0
Adenosine receptor A1 and Adenosine receptor A2a ligand AGN-PC... 2 25
Hydroxycarboxylic acid receptor 2 and Hydroxycarboxylic acid r... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26406 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543