CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17684
Family Name Melatonin receptor type 1B and Melatonin receptor type 1A ligand AGN-PC-077LH6 family
No. of Seeds 5 No. of Other Members 5
Family Centroid CFAMM00179359 Functional Category Bioactive with Natural Product
Superfamily Fatty-acid amide hydrolase 1 Inhibitor Phenylcarbamic Acid Biphenyl-3-yl Ester Superfamily
Class Class 615

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 61 433
Squalene monooxygenase Inhibitor Tolnaftate Family 1 4
Melatonin receptor type 1A Ligand Agomelatine Family 12 164
Dapoxetine family 3 40
Dihydroorotate dehydrogenase and Interleukin-17A Inhibitor Vid... 4 74
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
Voltage-dependent L-type calcium channel Ligand Sq32,910 Family 1 25
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Multidrug resistance protein Inhibitor MM36 Family 1 1
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 131
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Alpha-1A adrenergic receptor Ligand Naftopidil Family 15 119
Cannabinoid receptor 1 Ligand N-(4-methoxyphenyl)oleamide Family 4 23
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 12 46
Alpha-1A adrenergic receptor and D(2) dopamine receptor Ligand... 5 49
Histone deacetylase 2 Inhibitor N-(4-amino-3'-methoxybiphenyl-... 3 49
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
5-hydroxytryptamine receptor 2A Ligand 3-methoxy-9-aminomethyl... 7 14
Fatty-acid amide hydrolase 1 Inhibitor N-butylcarbamic Acid Bi... 9 31
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Proto-oncogene tyrosine-protein kinase receptor Ret Ligand (z)... 1 60
Fatty-acid amide hydrolase 1 Inhibitor Phenylcarbamic Acid Bip... 3 7
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
5-hydroxytryptamine receptor 1A Ligand 9-methoxy-1,2,3,4-tetra... 7 10
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
Fatty-acid amide hydrolase 1 Inhibitor 8-phenyloctylcarbamic A... 12 1
Liver carboxylesterase 1 Inhibitor SCH-48375 Family 2 28
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 2 6
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
Substance-P receptor ligand N-[1-[acetyl-[(2-methoxyphenyl)met... 3 9
Cathepsin K inhibitor N-[(2S)-1-(4-methoxyanilino)propan-2-yl]... 11 10
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 6 19
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 1 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 14 12
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 8 0
Melatonin receptor type 1A ligand [7-methoxy-1-[2-(propanoylam... 3 0
Transient receptor potential cation channel subfamily V member... 3 15
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 3
D(4) dopamine receptor and D(3) dopamine receptor ligand SureC... 5 0
C5a anaphylatoxin chemotactic receptor 1 ligand N-[(4-dimethyl... 1 4
Prostaglandin D2 receptor 2 ligand SureCN136287 family 1 9
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 11 4
5-hydroxytryptamine receptor 1A and D(4) dopamine receptor lig... 1 0
Sphingosine 1-phosphate receptor 1 ligand 2-methoxy-N-[(4-phen... 2 23
Free fatty acid receptor 1 ligand 3-[4-[[3-[4-(2-ethylsulfonyl... 5 4
Integrin beta-3 and Integrin alpha-2 inhibitor 3-(4-methoxyphe... 4 6
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 2 0
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 2 4
E3 ubiquitin-protein ligase XIAP and Cytochrome P450 3A4 inhib... 1 2
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 2 11
C-C chemokine receptor type 5 ligand dimethyl-[[4-[[7-(4-methy... 7 8
Capsid scaffolding protein inhibitor AC1MHP1L family 3 6
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 0
Neuropeptide Y receptor type 5 ligand 3-[4-(4-fluorophenoxy)ph... 4 0
Neuropeptide Y receptor type 5 ligand 1-[1-(4-fluorophenyl)pro... 2 8
Neuropeptide Y receptor type 5 ligand AGN-PC-01NRZ6 family 3 6
P2X purinoceptor 7 inhibitor 2-(1-adamantyl)-N-(3-methoxy-2-me... 2 4
Melanin-concentrating hormone receptor 1 and D(2) dopamine rec... 1 0
Mitogen-activated protein kinase 14 inhibitor SureCN4822166 fa... 1 4
Histamine H3 receptor ligand SureCN3057839 family 1 0
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 0
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 1 0
Mitogen-activated protein kinase 14 inhibitor ITX 5061 free ba... 2 3
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 1 0
D(4) dopamine receptor and Alpha-1B adrenergic receptor ligand... 1 1
Protein-S-isoprenylcysteine O-methyltransferase inhibitor N-[2... 1 2
Bile acid receptor ligand methyl (E)-3-[3-[[4-(2,6-dimethoxyph... 2 6
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 2 3
Acetylcholinesterase and Butyrylcholinesterase inhibitor AGN-P... 3 0
N-(4-acetamidophenyl)-2-(2,2-dimethyl-3,4-dihydrochromen-6-yl)... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26816 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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