CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17692
Family Name Prostaglandin E2 receptor EP3 subtype and Prostaglandin F2-alpha receptor ligand (E)-3-[1-[(3,4-difluorophenyl)methyl]-3a-methyl-2-oxo-3,4,5,6-tetrahydroindol-7-yl]-N-(2,4,5-trifluorophenyl)sulfonylprop-2-enamide family
No. of Seeds 5 No. of Other Members 1
Family Centroid CFAMM00443952 Functional Category Bioactive
Superfamily Prostaglandin F2-alpha receptor and Prostaglandin E2 receptor EP3 subtype Binder Superfamily 2
Class Class 1321

Cousin Family NamesSeedsMembers
Potassium voltage-gated channel subfamily A member 5 Ligand N-... 8 32
Prostaglandin E2 receptor EP3 subtype ligand (E)-3-[1-[(2,4-di... 20 3
Prostaglandin E2 receptor EP3 subtype ligand (E)-3-[1-(naphtha... 13 5
Prostaglandin E2 receptor EP3 subtype ligand (E)-N-(3,4-dichlo... 8 0
Prostaglandin E2 receptor EP3 subtype and Prostaglandin F2-alp... 7 2
Prostaglandin E2 receptor EP3 subtype and Prostaglandin F2-alp... 7 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00443952 CHEMBL479263 Bioactive (E)-3-[1-[(3,4-difluorophenyl)methyl]-3a-methyl-2-oxo-3,4,5,6-tetrahydroindol-7-yl]-N-(2,4,5-trifluorophenyl)sulfonylprop-2-enamide
CFAMM00443951 CHEMBL482318 Bioactive (E)-3-[1-[(3,4-difluorophenyl)methyl]-3a-methyl-2-oxo-3,4,5,6-tetrahydroindol-7-yl]-N-(3,5-difluorophenyl)sulfonylprop-2-enamide
CFAMM00443950 CHEMBL481823 Bioactive (E)-N-(3,4-difluorophenyl)sulfonyl-3-[1-[(4-fluorophenyl)methyl]-3a-methyl-2-oxo-3,4,5,6-tetrahydroindol-7-yl]prop-2-enamide
CFAMM00443955 CHEMBL479664 Bioactive (E)-3-[1-[(3,4-difluorophenyl)methyl]-3a-methyl-2-oxo-3,4,5,6-tetrahydroindol-7-yl]-N-(3,4-difluorophenyl)sulfonylprop-2-enamide
CFAMM00443954 CHEMBL480635 Bioactive 3-[1-[(3,4-difluorophenyl)methyl]-3a-methyl-2-oxo-3,4,5,6-tetrahydroindol-7-yl]-N-(2,4,5-trifluorophenyl)sulfonylpropanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27702 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543