CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17715
Family Name Dipeptidyl peptidase 4 inhibitor (2S,4S)-1-[2-[[1-[4-cyano-2-(trifluoromethyl)phenyl]piperidin-4-yl]amino]acetyl]-4-fluoropyrrolidine-2-carbonitrile family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00444061 Functional Category Bioactive
Superfamily Dipeptidyl peptidase 4 and Androgen receptor Binder Superfamily
Class Class 1613

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Sodium channel Ligand xylidine derivative Mepivacaine Family 10 114
Motilin receptor Ligand GSK962040 Family 30 457
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Androgen receptor Ligand LG-121071 Family 8 32
Aromatase Inhibitor 3-(4-amino-phenyl)-1-methyl-pyrrolidine-2,... 4 8
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 4 24
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 3 3
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 10
Androgen receptor and Progesterone receptor ligand (5bR,9aR)-1... 1 0
D(4) dopamine receptor ligand 1-Piperidineacetamide, 4-(2-cyan... 3 7
Dipeptidyl peptidase 4 inhibitor SureCN296150 family 3 8
Dipeptidyl peptidase 4 inhibitor (2S)-1-[(2S,4S)-4-anilinopyrr... 2 13
Kappa-type opioid receptor and Cytochrome P450 2D6 ligand Sure... 11 9
Neuropeptide Y receptor type 5 ligand 2-(5-fluoro-2,3-dihydroi... 4 3
Dipeptidyl peptidase 4 inhibitor 4-[4-[(3S,5S)-5-(1,3-thiazoli... 3 2
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 6
Histamine receptor H3 ligand N-[2-methyl-4-[(3S)-3-[(2S)-2-met... 10 7
Dipeptidyl peptidase 4 inhibitor 4-[[(3S,5S)-5-[(2S)-2-cyanopy... 4 12
Cathepsin K and Cathepsin B inhibitor AGN-PC-076LFZ family 1 0
Metabotropic glutamate receptor 2 ligand 4-[4-(methylamino)phe... 1 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00444061 CHEMBL480716 Bioactive (2S,4S)-1-[2-[[1-[4-cyano-2-(trifluoromethyl)phenyl]piperidin-4-yl]amino]acetyl]-4-fluoropyrrolidine-2-carbonitrile
CFAMM00444060 CHEMBL480903 Bioactive SureCN5215366

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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