CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17717
Family Name Histamine H3 receptor ligand SureCN1382602 family
No. of Seeds 6 No. of Other Members 0
Family Centroid CFAMM00444075 Functional Category Bioactive
Superfamily Histamine H1 receptor Ligand Alcaftadine Superfamily
Class Class 715

Cousin Family NamesSeedsMembers
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
14-alpha sterol demethylase Inhibitor Butoconazole Family 2 53
Kappa-type opioid receptor Ligand Brl 52974 Family 2 27
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Cannabinoid receptor 1 Ligand 1-(4-chlorophenyl)-2-(2,4-dichlo... 18 41
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor Su... 16 5
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 6 14
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 2 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 2 7
Sodium- and chloride-dependent glycine transporter 1 and Sodiu... 4 8
P2X purinoceptor 7 inhibitor SureCN109432 family 10 28
P2X purinoceptor 7 inhibitor SureCN113576 family 2 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 6 5
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 2 1
Histamine H3 receptor ligand SureCN3534043 family 3 3
Histidinol dehydrogenase inhibitor (3S)-3-amino-1-(3,4-dichlor... 2 1
Histamine H3 receptor ligand [3-methyl-2-[(1-propan-2-ylpiperi... 5 3
Centromere-associated protein E inhibitor 5-bromo-N-[(3,4-dich... 1 0


External ID

Functional Category

Molecule Name

CFAMM00444075 CHEMBL481745 Bioactive SureCN1382602
CFAMM00444074 CHEMBL521415 Bioactive SureCN1384478
CFAMM00444073 CHEMBL519951 Bioactive SureCN1381819
CFAMM00444072 CHEMBL480829 Bioactive SureCN1384369
CFAMM00444071 CHEMBL521256 Bioactive (4-chlorophenyl)-[3-methyl-2-(4-piperidin-1-ylbutyl)imidazol-4-yl]methanone
CFAMM00444076 CHEMBL520100 Bioactive AGN-PC-00BAA7

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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