CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17738
Family Name Tyrosine-protein kinase ITK/TSK and Insulin receptor ligand AGN-PC-04XL7G family
No. of Seeds 7 No. of Other Members 11
Family Centroid CFAMM00429742 Functional Category Bioactive
Superfamily Insulin receptor and Tyrosine-protein kinase ITK/TSK Binder Superfamily
Class Class 1692

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase Chk1 Inhibitor AZD7762 Family 26 90
Histone deacetylase 1 and Potassium voltage-gated channel subf... 4 36
Prelamin-A/C and Niemann-Pick C1 protein inhibitor CHEMBL13592... 1 16
Kinesin-like protein KIF11 inhibitor N-(3-aminopropyl)-N-[1-(3... 2 22
Calcitonin gene-related peptide type 1 receptor and Cytochrome... 4 7
Melanin-concentrating hormone receptor 1 and Muscarinic acetyl... 8 2
Tyrosine-protein kinase ITK/TSK and Insulin receptor ligand N-... 1 12
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-00A4QJ family 12 6
Tyrosine-protein kinase ITK/TSK and Insulin receptor ligand N-... 2 17
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-04XL74 family 1 0
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-04XL6C family 2 0


External ID

Functional Category

Molecule Name

CFAMM00444150 CHEMBL500349 Bioactive N-[1-(3-amino-3-oxopropyl)-5-[benzoyl(methyl)amino]benzimidazol-2-yl]-5-[(E)-2-(4-aminophenyl)ethenyl]thiophene-2-carboxamide
CFAMM00444163 CHEMBL507769 Bioactive N-[1-(3-amino-3-oxopropyl)-5-[benzoyl(methyl)amino]benzimidazol-2-yl]-5-[(E)-2-(2-aminophenyl)ethenyl]thiophene-2-carboxamide
CFAMM00444155 CHEMBL519250 Bioactive N-[1-(3-amino-3-oxopropyl)-5-[benzoyl(methyl)amino]benzimidazol-2-yl]-5-[(E)-2-cyanoethenyl]thiophene-2-carboxamide
CFAMM00444161 CHEMBL499247 Bioactive N-[1-(3-amino-3-oxopropyl)-5-[benzoyl(methyl)amino]benzimidazol-2-yl]-5-[(E)-2-(3-aminophenyl)ethenyl]thiophene-2-carboxamide
CFAMM00444153 CHEMBL487786 Bioactive methyl (E)-3-[5-[[1-(3-amino-3-oxopropyl)-5-[benzoyl(methyl)amino]benzimidazol-2-yl]carbamoyl]thiophen-2-yl]prop-2-enoate
CFAMM00444151 CHEMBL482169 Bioactive AGN-PC-04XL6S

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



59194 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543