CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17739
Family Name Growth hormone secretagogue receptor type 1 ligand [(3R)-3-aminopyrrolidin-1-yl]-[(2S)-1-[4-(2,5-dichlorophenyl)phenyl]sulfonylpiperidin-2-yl]methanone family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00444168 Functional Category Bioactive
Superfamily Coagulation factor X and Growth hormone secretagogue receptor type 1 Binder Superfamily
Class Class 4312

Cousin Family NamesSeedsMembers
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
Prothrombin Inhibitor D-leucyl-n-(3-chlorobenzyl)-l-prolinamid... 18 168
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 6 19
Calpain-1 catalytic subunit inhibitor 6-chloro-2-methyl-1,1-di... 3 9
Cathepsin L1 and Cathepsin B inhibitor (2S)-3-methyl-N-[(2S)-4... 7 24
Collagenase 3 and Stromelysin-1 inhibitor (2R,4S)-N-hydroxy-4-... 2 4
Coagulation factor X and Tissue-type plasminogen activator inh... 2 29
Coagulation factor X inhibitor (2S)-N-(3-aminopropyl)-2-[(3S)-... 22 15
Coagulation factor X inhibitor 2-[(6-chloronaphthalen-2-yl)sul... 10 2
Growth hormone secretagogue receptor type 1 ligand [(3S)-3-ami... 2 6
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor N-... 9 0
Aldose reductase inhibitor 4-chloro-2-(2,5-dioxoimidazolidin-4... 4 22


External ID

Functional Category

Molecule Name

CFAMM00444169 CHEMBL561322 Bioactive SureCN8289127
CFAMM00444168 CHEMBL482220 Bioactive [(3R)-3-aminopyrrolidin-1-yl]-[(2S)-1-[4-(2,5-dichlorophenyl)phenyl]sulfonylpiperidin-2-yl]methanone

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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