CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17740
Family Name Growth hormone secretagogue receptor type 1 ligand N-benzyl-2-(3-chlorophenoxy)-N-[[(2R)-pyrrolidin-2-yl]methyl]propanamide family
No. of Seeds 5 No. of Other Members 19
Family Centroid CFAMM00444188 Functional Category Bioactive
Superfamily Menin and Beta-lactamase Binder Superfamily 25
Class Class 1140

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase PLK1 Inhibitor On Fa... 16 138
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
Beta-3 adrenergic receptor Ligand Amibegron Family 8 46
C-C chemokine receptor type 1 Ligand BX-471 Family 10 67
Extracellular calcium-sensing receptor Ligand Nps 568 Family 5 54
Prothrombin and Tissue-type plasminogen activator inhibitor CH... 10 5
E3 ubiquitin-protein ligase XIAP inhibitor N-METHYLALANYL-3-ME... 3 14
Regulator of G-protein signaling 12 and Beta-lactamase inhibit... 1 7
Prothrombin and Tissue-type plasminogen activator inhibitor CH... 11 4
Prostaglandin D2 receptor 2 ligand SureCN1713638 family 2 1
Kappa-type opioid receptor and Cytochrome P450 2D6 ligand Sure... 4 3
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand N-[(2... 10 12
Plasmepsin-2 and Cathepsin D inhibitor N-[2-(1,3-benzodioxol-5... 4 0
Prothrombin and Trypsin-1 inhibitor AGN-PC-073O5X family 3 1
Kappa-type opioid receptor ligand AGN-PC-03TFVP family 1 10
Cathepsin K and Cathepsin L1 inhibitor dipeptidyl nitrile, 16c... 1 0
Scytalone dehydratase inhibitor 2-cyano-N-[(1S,2R)-1-(2-cyanop... 5 0
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 2 2
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 0


External ID

Functional Category

Molecule Name

CFAMM00444176 CHEMBL489818 Bioactive (2S)-N-benzyl-2-(3-chlorophenoxy)-N-[[(2R)-pyrrolidin-2-yl]methyl]propanamide
CFAMM00444183 CHEMBL482420 Bioactive 2-(3-chlorophenoxy)-N-[(2-methylphenyl)methyl]-N-[[(2R)-pyrrolidin-2-yl]methyl]propanamide
CFAMM00444174 CHEMBL488965 Bioactive SureCN5355598
CFAMM00444188 CHEMBL489370 Bioactive N-benzyl-2-(3-chlorophenoxy)-N-[[(2R)-pyrrolidin-2-yl]methyl]propanamide
CFAMM00444192 CHEMBL519322 Bioactive (2S)-2-(3-chlorophenoxy)-N-[(2-methylphenyl)methyl]-N-[[(2R)-pyrrolidin-2-yl]methyl]propanamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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