CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17755
Family Name Corticotropin-releasing factor receptor 1 ligand AGN-PC-068CCI family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00444257 Functional Category Bioactive
Superfamily Cannabinoid receptor 2 and Cannabinoid receptor 1 Binder Superfamily 26
Class Class 795

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 29 421
Insulin-like growth factor 1 receptor Ligand AEW-541 Family 12 140
Corticotropin-releasing factor receptor 1 Ligand GSK561679 Family 5 6
Corticotropin-releasing factor receptor 1 Ligand Dmp-695/696 F... 11 20
Vascular endothelial growth factor receptor 2 Ligand L00002164... 6 23
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 19 48
Corticotropin-releasing factor receptor 1 Ligand BMS-561388 Fa... 10 16
Serine/threonine-protein kinase B-raf inhibitor SureCN1015955 ... 17 18
Corticotropin-releasing factor receptor 1 ligand AGN-PC-068CC4... 20 7
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor Su... 2 16
Epidermal growth factor receptor and Cyclin-dependent kinase 1... 3 4
Proto-oncogene tyrosine-protein kinase Src and Phosphatidylino... 4 20
Tyrosine-protein kinase ABL1 and Tyrosine-protein kinase HCK i... 2 2
Translocator protein inhibitor AGN-PC-080ILF family 9 3
Cellular tumor antigen p53 inhibitor CHEMBL1401545 family 1 25
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 4
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 6
Tyrosine-protein kinase JAK2 inhibitor 5-(3-methoxyphenyl)-N-[... 2 11
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 5 1
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 8 17
Neuropeptide Y receptor type 1 ligand CP-671906 family 10 0
Calmodulin-domain protein kinase 1 and Tyrosine-protein kinase... 5 5
Corticotropin-releasing factor receptor 1 ligand AGN-PC-005GB4... 6 3
Corticotropin-releasing factor receptor 1 ligand CHEMBL1819076... 2 0
Corticotropin-releasing factor receptor 1 ligand 5-N-(2-chloro... 7 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 17
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 6 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 4 4
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 4 0
Estrogen receptor and Estrogen receptor beta ligand 4-[3-[4-(2... 1 0
cGMP-dependent 3',5'-cyclic phosphodiesterase inhibitor SureCN... 4 0
Cathepsin K and Cathepsin S inhibitor SureCN4135077 family 2 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 3-(4-... 3 1
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 2 6
Adenosine receptor A2a ligand AGN-PC-077RYH family 16 5
Corticotropin-releasing factor receptor 1 ligand AGN-PC-068CCL... 3 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00444259 CHEMBL482981 Bioactive AGN-PC-068CCH
CFAMM00444258 CHEMBL482983 Bioactive AGN-PC-068CCJ
CFAMM00444257 CHEMBL482982 Bioactive AGN-PC-068CCI

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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