CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17756
Family Name Neuropeptide Y receptor type 5 ligand 1'-(5H-[1,3]dioxolo[4,5-f]benzimidazol-6-yl)spiro[2-benzofuran-3,4'-piperidine]-1-one family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00444262 Functional Category Bioactive
Superfamily TGF-beta receptor type-1 and Telomerase reverse transcriptase Binder Superfamily
Class Class 1456

Cousin Family NamesSeedsMembers
TGF-beta receptor type-1 Ligand SB-431542 Family 2 42
Vascular endothelial growth factor receptor 2 and Fibroblast g... 1 6
Mast/stem cell growth factor receptor Kit and Serine/threonine... 11 29
Insulin-like growth factor 1 receptor ligand SureCN311483 family 3 0
Neuropeptide Y receptor type 5 ligand AGN-PC-02WBQH family 7 1
Neuropeptide Y receptor type 5 ligand AGN-PC-077LX1 family 8 1
Dihydrofolate reductase inhibitor AGN-PC-073PP8 family 1 0


External ID

Functional Category

Molecule Name

CFAMM00444262 CHEMBL483040 Bioactive 1'-(5H-[1,3]dioxolo[4,5-f]benzimidazol-6-yl)spiro[2-benzofuran-3,4'-piperidine]-1-one
CFAMM00444261 CHEMBL483244 Bioactive 1'-(2,2-difluoro-5H-[1,3]dioxolo[4,5-f]benzimidazol-6-yl)spiro[2-benzofuran-3,4'-piperidine]-1-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



87459 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543