CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1778
Family Name Cysteinyl leukotriene receptor 1 ligand 4-[(2S)-2-[[7-(quinolin-2-ylmethoxy)naphthalen-2-yl]sulfonylamino]propyl]benzoic acid family
No. of Seeds 6 No. of Other Members 15
Family Centroid CFAMM00327279 Functional Category Bioactive
Superfamily Cysteinyl leukotriene receptor 1 and B2 bradykinin receptor Binder Superfamily
Class Class 1637

Cousin Family NamesSeedsMembers
Arachidonate 5-lipoxygenase-activating protein Inhibitor DG031... 3 206
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 22 57
Neuromedin-K receptor and Substance-K receptor ligand 2-[2-phe... 2 2
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 4 20
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 18
Somatostatin receptor type 5 and Somatostatin receptor type 1 ... 2 8
Cysteinyl leukotriene receptor 1 ligand SureCN7808360 family 4 11
Cysteinyl leukotriene receptor 1 ligand SureCN9053715 family 2 11
B2 bradykinin receptor ligand SureCN7012818 family 1 2
Cysteinyl leukotriene receptor 1 ligand AGN-PC-075KCE family 5 33
B2 bradykinin receptor ligand SureCN6640854 family 7 4
Prostaglandin D2 receptor 2 ligand SureCN137822 family 3 0
Cysteinyl leukotriene receptor 2 and Cysteinyl leukotriene rec... 16 5
Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[... 15 2
Cysteinyl leukotriene receptor 1 and Peripheral myelin protein... 1 1
Collagenase 3 and A disintegrin and metalloproteinase with thr... 5 6
Arachidonate 5-lipoxygenase-activating protein inhibitor methy... 12 3
Disintegrin and metalloproteinase domain-containing protein 17... 16 2
Prostaglandin E synthase inhibitor 3-[4-(3-cyanopropoxy)-3-met... 2 4
Cholinesterase and Acetylcholinesterase inhibitor 6-[4-[2-fluo... 17 0
Arachidonate 5-lipoxygenase-activating protein inhibitor 2-[[4... 7 4
Cysteinyl leukotriene receptor 1 ligand 4-oxo-7-[[3-(quinolin-... 4 17
Prothrombin and Trypsin-1 inhibitor AGN-PC-074I4I family 3 1
Prothrombin inhibitor AGN-PC-074I2Z family 2 1
Proteinase-activated receptor 1 ligand 2-[2-[(E)-2-[(3R,3aS,4S... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00327296 CHEMBL128641 Bioactive AGN-PC-075KFF
CFAMM00327294 CHEMBL128583 Bioactive SureCN8733757
CFAMM00327287 CHEMBL128317 Bioactive SureCN8732748
CFAMM00327293 CHEMBL337195 Bioactive SureCN8735894
CFAMM00327286 CHEMBL335000 Bioactive AGN-PC-075KFP
CFAMM00327279 CHEMBL1214530 Bioactive 4-[(2S)-2-[[7-(quinolin-2-ylmethoxy)naphthalen-2-yl]sulfonylamino]propyl]benzoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543