CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17782
Family Name Bifunctional epoxide hydrolase 2 and Cytochrome P450 2C9 inhibitor 6-fluoro-N-[(1S,2R)-2-phenylcyclopropyl]spiro[3,4-dihydrochromene-2,4'-piperidine]-1'-carboxamide family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00444366 Functional Category Bioactive
Superfamily Menin and Cytochrome P450 2C9 Binder Superfamily 2
Class Class 1211

Cousin Family NamesSeedsMembers
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
5-hydroxytryptamine receptor 2A Ligand Pimavanserin Family 4 23
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Histamine H3 receptor Ligand UCL-2138 Family 23 172
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 13
5-hydroxytryptamine receptor 2A Ligand C-(9h-xanthen-9-yl)-met... 3 5
Histamine H1 receptor and Arachidonate 5-lipoxygenase Ligand N... 5 6
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 1 13
Substance-P receptor ligand AGN-PC-075NP5 family 4 8
Baculoviral IAP repeat-containing protein 3 and E3 ubiquitin-p... 7 1
C-C chemokine receptor type 3 and C-C chemokine receptor type ... 3 4
C-C chemokine receptor type 1 ligand SureCN8184421 family 11 10
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 1 0
Bifunctional epoxide hydrolase 2 and Epoxide hydrolase 1 inhib... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00444366 CHEMBL483876 Bioactive 6-fluoro-N-[(1S,2R)-2-phenylcyclopropyl]spiro[3,4-dihydrochromene-2,4'-piperidine]-1'-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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