CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17783
Family Name Prostaglandin E synthase inhibitor AGN-PC-014WPB family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00444368 Functional Category Bioactive
Superfamily Adenosine receptor A3 Ligand 2-(5-chloro-1h-benzo[d]imidazol-2-yl)quinoxaline Superfamily
Class Class 2257

Cousin Family NamesSeedsMembers
Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family 32 639
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Fibroblast growth factor receptor 2 and Fibroblast growth fact... 11 86
Cannabinoid receptor 1 Ligand CP-945598 Family 18 173
HCV NS4B protein Inhibitor Clemizole Family 2 43
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Histamine H3 receptor Ligand SCH79687 Family 11 29
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2,6-di... 13 14
Adenosine receptor A3 Ligand 2,6-bis(4-chlorophenyl)-9h-purine... 4 12
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Arachidonate 5-lipoxygenase Inhibitor 2,4,5-triarylimidazole A... 3 16
Epidermal growth factor receptor Ligand (3-bromo-phenyl)-quina... 7 5
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Mitogen-activated protein kinase 3 and RAF proto-oncogene seri... 8 5
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
Dipeptidyl peptidase 4 Inhibitor (5-phenyl-3h-benzo[d]imidazol... 5 13
Mitogen-activated protein kinase kinase kinase 8 and Stromelys... 6 53
Aromatase and Cytochrome P450 26A1 Inhibitor Liarozole Family 4 1
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Glycogen synthase kinase-3 beta Inhibitor CHIR-98023 Family 5 6
Glycogen synthase kinase-3 beta Inhibitor 4-(5-bromo-1h-indol-... 7 18
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-bromobenzyl... 3 0
RAF proto-oncogene serine/threonine-protein kinase and Serine/... 3 5
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 1 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 5 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Nuclear rec... 9 6
Cannabinoid receptor 2 ligand 8-(2-chlorophenyl)-9-cyclopropyl... 4 5
Transient receptor potential cation channel subfamily V member... 4 0
Methionine--tRNA ligase inhibitor N-[(4R)-6,8-dibromo-1,2,3,4-... 1 1
Smoothened homolog inhibitor N-[4-chloro-3-(5-phenyl-1H-imidaz... 4 1
Receptor-type tyrosine-protein kinase FLT3 and Aurora kinase A... 2 0
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 6 3
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 5 2
RAF proto-oncogene serine/threonine-protein kinase and Serine/... 4 3
Mitogen-activated protein kinase 14 inhibitor 5-[2-(2,6-dichlo... 1 0
Serine/threonine-protein kinase B-raf inhibitor 1-[2-[[4-[2-cy... 2 0
Cannabinoid receptor 1 ligand AGN-PC-07CPJ5 family 9 14
Prostaglandin E synthase inhibitor 7-bromo-2-(2-chlorophenyl)-... 3 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00444368 CHEMBL483894 Bioactive AGN-PC-014WPB

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26821 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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