CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17802
Family Name Cell division cycle 7-related protein kinase and Cyclin-dependent kinase 9 inhibitor (5Z)-2-(benzylamino)-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylidene)-1,3-thiazol-4-one family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00388511 Functional Category Bioactive
Superfamily RAC-gamma serine/threonine-protein kinase Inhibitor AZD5363 Superfamily
Class Class 1234

Cousin Family NamesSeedsMembers
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Translocator protein Inhibitor Emapunil Family 7 89
RAC-gamma serine/threonine-protein kinase Inhibitor AZD5363 Fa... 35 69
Vascular endothelial growth factor receptor 2 Ligand XL999 Family 11 87
D(4) dopamine receptor Ligand L-745,870 Family 30 205
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Olprin... 2 7
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Proto-oncogene tyrosine-protein kinase Src Inhibitor 5,7-diphe... 2 11
Prothrombin inhibitor SureCN5856722 family 3 16
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 12
RAC-alpha serine/threonine-protein kinase inhibitor SureCN4728... 11 6
RAC-alpha serine/threonine-protein kinase and Proline-rich AKT... 2 4
Prelamin-A/C and Lethal(3)malignant brain tumor-like protein 1... 1 1
Histone deacetylase 1 inhibitor (E)-N-hydroxy-3-[4-[[2-(1H-pyr... 2 8
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206623 family 10 11
Cell division cycle 7-related protein kinase and Protein DBF4 ... 15 7
Cell division cycle 7-related protein kinase and Dual specific... 3 1
Protein kinase C theta type and Leucine-rich repeat serine/thr... 1 1
5-hydroxytryptamine receptor 2B ligand SureCN1299437 family 6 7
RAC-alpha serine/threonine-protein kinase and RAC-gamma serine... 20 7
LIM domain kinase 2 inhibitor 3-[[(cyanoamino)-[(2S)-2-methyl-... 6 0
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00444454 CHEMBL484991 Bioactive (5Z)-2-(propan-2-ylamino)-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylidene)-1,3-thiazol-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27752 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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