CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17803
Family Name Pteridine reductase, putative inhibitor 1-[(3,4-dichlorophenyl)methyl]-7-phenylbenzimidazol-2-amine family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00444455 Functional Category Bioactive
Superfamily HCV NS4B protein Inhibitor Clemizole Superfamily
Class Class 1172

Cousin Family NamesSeedsMembers
Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family 32 639
Benzodiazepine receptor Ligand Midazolam Family 5 160
Histamine H1 receptor Ligand Mizolastine Family 14 603
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
HCV NS4B protein Inhibitor Clemizole Family 2 43
Tryptase Inhibitor Babim Family 12 90
Histamine H3 receptor and Histamine H4 receptor Ligand Clobenp... 31 38
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Histamine H3 receptor Ligand SCH79687 Family 11 29
Adenosine receptor A3 Ligand 2,6-bis(4-chlorophenyl)-9h-purine... 4 12
Adenosine receptor A3 Ligand 2-(5-chloro-1h-benzo[d]imidazol-2... 7 51
Dipeptidyl peptidase 4 Inhibitor (5-phenyl-3h-benzo[d]imidazol... 5 13
Aromatase and Cytochrome P450 26A1 Inhibitor Liarozole Family 4 1
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Cytochrome P450 11B1, mitochondrial Inhibitor 1-(4-bromobenzyl... 3 0
Sodium channel protein type 1 subunit alpha and Sodium channel... 10 14
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 3
Melanin-concentrating hormone receptor 1 and Potassium voltage... 8 27
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 1
D(4) dopamine receptor and D(2) dopamine receptor ligand 4-met... 13 8
Histamine H4 receptor ligand (2Z)-5-chloro-2-[(1-methylpiperid... 2 8
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 5 0
Transient receptor potential M8 protein ligand 2-[(E)-2-(oxan-... 5 3
Melanin-concentrating hormone receptor 1 ligand SureCN3334191 ... 4 7
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 3
Progesterone receptor ligand AGN-PC-00B9AT family 4 4
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 10 6
Cannabinoid receptor 2 ligand 8-(2-chlorophenyl)-9-cyclopropyl... 4 5
Melanin-concentrating hormone receptor 1 ligand 3-[(1R,3R,6S)-... 2 4
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 6 3
Mitogen-activated protein kinase 10 inhibitor CYCLOPROPYL-{4-[... 2 1
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 2
Neuropeptide Y receptor type 5 ligand SureCN6835211 family 1 2
Dipeptidyl peptidase 4 inhibitor 7-(aminomethyl)-6-(2-chloroph... 2 5
Substance-K receptor ligand SureCN9035669 family 10 5
C-C chemokine receptor type 5 ligand 1-[4-(3-chlorophenyl)-4-[... 3 1
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Nociceptin receptor and Mu-type opioid receptor ligand 2-(3-ch... 2 0
Progesterone receptor ligand 3-benzyl-5-(3-nitrophenyl)-1H-ben... 1 2
P2X purinoceptor 7 inhibitor N-benzyl-1-(2,3-dichlorophenyl)te... 19 0
Small conductance calcium-activated potassium channel protein ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00444455 CHEMBL484995 Bioactive 1-[(3,4-dichlorophenyl)methyl]-7-phenylbenzimidazol-2-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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