CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17811
Family Name Mitogen-activated protein kinase 14 and Dual specificity mitogen-activated protein kinase kinase 1 inhibitor SureCN3524366 family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00444493 Functional Category Bioactive
Superfamily Mitogen-activated protein kinase 14 and B1 bradykinin receptor Binder Superfamily
Class Class 3143

Cousin Family NamesSeedsMembers
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Bifunctional epoxide hydrolase 2 Inhibitor N-(naphthalen-2-yl)... 11 57
Prelamin-A/C inhibitor CHEMBL1395532 family 1 10
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-2-[(4-fluo... 7 1
Integrin beta-1 and Integrin alpha-5 inhibitor SureCN14453385 ... 5 0
Peroxisome proliferator-activated receptor gamma and Cytochrom... 1 1
Neuronal acetylcholine receptor subunit alpha-4 ligand AGN-PC-... 2 2
Serine/threonine-protein kinase PLK2 and Serine/threonine-prot... 1 0
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07CPKU family 1 3
Serine/threonine-protein kinase PLK1 inhibitor 3db8 family 1 0
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07CPNI family 3 3


External ID

Functional Category

Molecule Name

CFAMM00444493 CHEMBL485286 Bioactive SureCN3524366
CFAMM00444494 CHEMBL596248 Bioactive (2S)-3-[4-[3-[[(4-methylpyridin-2-yl)amino]methyl]-1,2-oxazol-5-yl]phenyl]-2-[(2,4,6-trimethylbenzoyl)amino]propanoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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