CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17814
Family Name Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-077RCV family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00444502 Functional Category Bioactive
Superfamily Acyl-CoA desaturase and Tyrosine-protein kinase ITK/TSK Binder Superfamily
Class Class 4773

Cousin Family NamesSeedsMembers
Gamma-secretase subunit APH-1B Inhibitor E2012 Family 3 67
Poly [ADP-ribose] polymerase 1 Inhibitor 2-(3'-methoxyphenyl) ... 9 93
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 6 8
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 4 4
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 3 0
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 10 46
Metabotropic glutamate receptor 5 Ligand 3-methoxy-n-(6-methyl... 3 15
DNA-(apurinic or apyrimidinic site) lyase and Nuclear receptor... 2 10
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 9
Thyroid hormone receptor beta and Ferritin light chain ligand ... 1 35
Thyroid hormone receptor beta and Cruzipain ligand CHEMBL14730... 1 12
Melanocortin receptor 4 ligand AGN-PC-076AML family 3 24
Serine/threonine-protein kinase PLK1 inhibitor AGN-PC-0A9RFQ f... 2 1
MAP kinase-activated protein kinase 2 inhibitor N-[4-(4-oxospi... 3 0
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 8
Nitric oxide synthase, inducible inhibitor 2-[1-(2-imidazol-1-... 4 3
Glycogen synthase kinase-3 beta and Casein kinase I isoform ga... 3 0
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4461871 f... 2 2
Melanocortin receptor 4 ligand AGN-PC-076AMT family 2 9
Gonadotropin-releasing hormone receptor ligand AGN-PC-074DFG f... 2 1
Cannabinoid receptor 2 ligand AGN-PC-03LKW5 family 24 5
RAF proto-oncogene serine/threonine-protein kinase inhibitor a... 8 6
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-077RDJ family 15 1
5-hydroxytryptamine receptor 2B ligand SureCN1299002 family 2 8
Tyrosine-protein kinase ITK/TSK and Insulin receptor ligand AG... 5 1
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07C5JC family 1 3
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00444502 CHEMBL485626 Bioactive AGN-PC-077RCV

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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