CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17820
Family Name Smoothened homolog inhibitor 2-(6-(4-(4-benzylphthalazin-1-yl)piperazin-1-yl)pyridin-3-yl)propan-2-ol family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00444528 Functional Category Bioactive
Superfamily Smoothened homolog inhibitor 2-(6-(4-(4-benzylphthalazin-1-yl)piperazin-1-yl)pyridin-3-yl)propan-2-ol Superfamily
Class Class 1149

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 2C ligand Tetracyclic antidepress... 14 498
Vascular endothelial growth factor receptor 2 Ligand Ptk787/zk... 5 38
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Polycystin-2 and Serine/threonine-protein kinase D1 inhibitor ... 4 12
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 7 9
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 5 0
Tyrosine-protein kinase Mer and Tyrosine-protein kinase recept... 5 3
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-[6-... 3 3


External ID

Functional Category

Molecule Name

CFAMM00444529 CHEMBL519219 Bioactive SureCN13444986
CFAMM00444528 CHEMBL485870 Bioactive 2-(6-(4-(4-benzylphthalazin-1-yl)piperazin-1-yl)pyridin-3-yl)propan-2-ol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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