CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17830
Family Name Calcitonin gene-related peptide type 1 receptor and Dual specificity mitogen-activated protein kinase kinase 2 ligand AGN-PC-07CQ3E family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00444637 Functional Category Bioactive
Superfamily Aldose reductase and Calcitonin gene-related peptide type 1 receptor Binder Superfamily
Class Class 1613

Cousin Family NamesSeedsMembers
Phospholipase D1 Inhibitor Halopemide Family 17 111
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07ZBI0 family 2 16
Calcitonin gene-related peptide type 1 receptor ligand N,N-dim... 12 32
Disintegrin and metalloproteinase domain-containing protein 17... 1 2
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 15 12
Calcitonin gene-related peptide type 1 receptor and Dual speci... 8 4
Oxytocin receptor ligand (2R)-2-[(2R,5R)-5-(2,3-dihydro-1H-ind... 2 0
Melanocortin receptor 4 ligand N-[(1S)-1-[2-[4-[(3S,4R)-4-(4-c... 26 13
Nociceptin receptor and Delta-type opioid receptor ligand spir... 25 9
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 4 1
Integrin beta-2 and Intercellular adhesion molecule 1 inhibito... 1 5
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 0
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 0
Aldose reductase inhibitor Spiro-cimqat family 6 8


External ID

Functional Category

Molecule Name

CFAMM00444640 CHEMBL571797 Bioactive N-[(3-chloro-5-fluorophenyl)methyl]-2,2-dimethyl-N-[2-[[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]amino]-2-oxoethyl]propanamide
CFAMM00444638 CHEMBL487244 Bioactive 2-(6-chloro-2-oxo-3H-benzimidazol-1-yl)-N-[(2R)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]acetamide
CFAMM00444637 CHEMBL568920 Bioactive AGN-PC-07CQ3E
CFAMM00444636 CHEMBL569588 Bioactive N-[(3,5-dichlorophenyl)methyl]-2,2-dimethyl-N-[2-[[(2S)-1'-methyl-2',4'-dioxospiro[1,3-dihydroindene-2,5'-imidazolidine]-5-yl]amino]-2-oxoethyl]propanamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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