CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1784
Family Name 5-hydroxytryptamine receptor 2A ligand AGN-PC-04RTMN family
No. of Seeds 7 No. of Other Members 5
Family Centroid CFAMM00327366 Functional Category Bioactive
Superfamily Nuclear receptor ROR-gamma and 5-hydroxytryptamine receptor 2A Binder Superfamily
Class Class 1032

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
TGF-beta receptor type-1 Ligand LY2157299 Family 13 56
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Adenosine receptor A3 Ligand 2-benzyl-2h-pyrazolo[3,4-c]quinol... 3 11
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Ripaze... 1 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 5 22
Orexin receptor type 2 and Orexin receptor type 1 ligand AGN-P... 7 19
Melanocortin receptor 4 and Melanocortin receptor 3 ligand N-[... 1 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 11
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 0
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-09M6D1 family 2 5
5-hydroxytryptamine receptor 3A ligand SureCN8035577 family 5 4
Serine/threonine-protein kinase 17A and Myosin light chain kin... 3 7
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 1
Histamine H3 receptor ligand N-methyl-N-[(3R)-1-propan-2-ylpyr... 3 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 4
Lysosomal Pro-X carboxypeptidase inhibitor [(3S,4R)-1-tert-but... 20 13
5-hydroxytryptamine receptor 4 ligand N-[(1R,5S)-8-[2-hydroxy-... 4 0
Coagulation factor X inhibitor AGN-PC-02WFR7 family 7 13
Cathepsin K and Cathepsin B inhibitor (1R,2R)-N-(1-cyanocyclop... 2 1
C-C chemokine receptor type 3 and Histamine H1 receptor ligand... 1 0
5-hydroxytryptamine receptor 3A ligand 5-hydroxy-1-methyl-N-[(... 4 2
5-hydroxytryptamine receptor 4 ligand 4-[2-[4-[[(1-propan-2-yl... 1 1
Coagulation factor X and Prothrombin inhibitor SureCN5819494 f... 5 8
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 2 3
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-(1-... 1 0
Metabotropic glutamate receptor 5 ligand 5-(4-fluorophenyl)-1,... 7 1
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 1 0
Cathepsin L1 and Cathepsin L2 inhibitor 5-tert-butyl-N-[(2S)-1... 2 5
Dipeptidyl peptidase 4 inhibitor (3R)-3-amino-1-(3-methyl-6,7-... 6 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor py... 1 3
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial ... 2 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 0
Vascular endothelial growth factor receptor 2 and Vascular end... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00327360 CHEMBL1214950 Bioactive AGN-PC-04RSV3
CFAMM00327357 CHEMBL1214947 Bioactive AGN-PC-04RTMT
CFAMM00327367 CHEMBL1214882 Bioactive AGN-PC-04RSJR
CFAMM00327354 CHEMBL1214731 Bioactive AGN-PC-04RSH0
CFAMM00327366 CHEMBL1214881 Bioactive AGN-PC-04RTMN
CFAMM00327361 CHEMBL1214878 Bioactive AGN-PC-04RT3W
CFAMM00327350 CHEMBL1214946 Bioactive AGN-PC-04RSGX

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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