CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17845
Family Name Serine/threonine-protein kinase Chk1 and Cyclin-dependent kinase 2-associated protein 1 inhibitor SureCN1563658 family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00444696 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase Chk1 and Cyclin-dependent kinase 7 Binder Superfamily
Class Class 3155

Cousin Family NamesSeedsMembers
Macrophage metalloelastase Inhibitor PF-00356231 Family 5 79
Histone deacetylase 1 Inhibitor N-hydroxy-5-(pyridin-3-yl)thio... 9 46
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(2... 2 20
Deoxycytidine kinase inhibitor N-[(1S,3S)-3-(4-amino-5-fluoro-... 2 5
Substance-K receptor ligand 6-methyl-N-[1-[[(2S)-1-phenyl-5-[4... 4 0
Muscarinic acetylcholine receptor M2 ligand AGN-PC-0745NK family 2 6
Sonic hedgehog protein inhibitor 3-chloro-N-[4-(methylamino)cy... 2 3
MAP kinase-activated protein kinase 2 inhibitor CHEMBL1231206 ... 6 7
Serine/threonine-protein kinase Chk1 inhibitor SureCN13010134 ... 7 29
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor lig... 2 8
Serine/threonine-protein kinase Chk1 inhibitor SureCN3070314 f... 16 32
Serine/threonine-protein kinase Chk1 inhibitor 2-(4-methoxyphe... 6 7
Serine/threonine-protein kinase Chk1 inhibitor 2-(1-methylindo... 3 4
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 8 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 9 1
Prostaglandin E2 receptor EP4 subtype ligand AGN-PC-09QJ7P family 2 0
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 1 2
Glycogen synthase kinase-3 beta inhibitor 7-(6-chloropyridin-2... 2 3
Neuronal acetylcholine receptor subunit alpha-7 ligand AGN-PC-... 7 1
Neuronal acetylcholine receptor subunit alpha-7 and Neuronal a... 8 5
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 2 2
Vascular endothelial growth factor receptor 1 and Receptor-typ... 1 0
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 15 8
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 2 8
Cell division cycle 7-related protein kinase and Protein DBF4 ... 2 1
Orexin receptor type 1 and Orexin receptor type 2 ligand N-[[(... 9 5
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 4 0
Nicotinamide phosphoribosyltransferase inhibitor N-[[4-(benzen... 4 4
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-01UBV6 f... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00444697 CHEMBL488231 Bioactive SureCN1562867
CFAMM00444696 CHEMBL488230 Bioactive SureCN1563658

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27396 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543