CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17846
Family Name Focal adhesion kinase 1 and Protein-tyrosine kinase 2-beta inhibitor AGN-PC-078WE8 family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00280433 Functional Category Bioactive
Superfamily Tyrosine-protein kinase BTK Inhibitor CC-292 Superfamily
Class Class 1334

Cousin Family NamesSeedsMembers
Dihydropterin pyrophosphokinase-dihydropteroate synthase inhib... 5 60
Dihydropterin pyrophosphokinase-dihydropteroate synthase inhib... 4 14
Mast/stem cell growth factor receptor Kit and Vascular endothe... 6 34
Neuropeptide Y receptor type 5 Ligand CGP71683A Family 5 74
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
Corticotropin-releasing factor receptor 1 Ligand CRA1000 Family 4 39
Interleukin-1 receptor type 1 and Mitogen-activated protein ki... 7 151
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Scytalone dehydratase Inhibitor Isoquinolin-1-yl-(3-phenyl-pro... 4 9
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Hepatocyte growth factor receptor Ligand 3-(phenylsulfonyl)-1h... 17 59
Prostaglandin G/H synthase 2 Inhibitor GW-637185X Family 27 48
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 22
Farnesyltransferase beta subunit, putative and Protein farnesy... 12 4
Corticotropin-releasing factor receptor 1 Ligand N-mesityl-6-m... 3 2
Acetylcholinesterase Inhibitor N-benzyl-2-morpholinopyrimidin-... 6 16
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07ZB89 family 6 13
Inhibitor of nuclear factor kappa-B kinase subunit beta inhibi... 1 7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 27
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 1 0
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 4 1
Growth hormone secretagogue receptor type 1 and Dihydrofolate ... 3 6
ALK tyrosine kinase receptor and Insulin receptor ligand N-[(1... 3 6
Fatty-acid amide hydrolase 1 inhibitor 5-[5-(4-chlorophenyl)su... 2 4
Neuropeptide Y receptor type 5 ligand SureCN8898853 family 2 3
Vascular endothelial growth factor receptor 2 ligand urea deri... 3 9
Vascular endothelial growth factor receptor 2 ligand urea deri... 2 0
Aurora kinase A and Aurora kinase B inhibitor 2-[[5-chloro-2-[... 3 7
Aurora kinase B and Vascular endothelial growth factor recepto... 1 2
Protein-tyrosine kinase 2-beta and Focal adhesion kinase 1 inh... 1 4
Growth hormone secretagogue receptor type 1 ligand AGN-PC-0760... 4 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 2-[4... 5 5
Serine/threonine-protein kinase SMG1 and Serine/threonine-prot... 10 0
Serine/threonine-protein kinase SMG1 and Cyclin-dependent kina... 3 1
Nicotinamide phosphoribosyltransferase and Cytochrome P450 2C9... 4 5
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 4 5
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor AG... 3 1
Cathepsin K and Cathepsin S inhibitor SureCN4138353 family 3 0
Prostaglandin G/H synthase 2 inhibitor 4-N,4-N-diethyl-2-(4-me... 5 1
Prostaglandin G/H synthase 2 inhibitor 6-ethoxy-2-(4-methylsul... 5 1
Prostaglandin G/H synthase 2 inhibitor 2-(4-methylsulfonylphen... 1 0
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 1 0
5-hydroxytryptamine receptor 6 ligand 8-(1-pyrrolidin-3-ylpyrr... 1 0
Ribosomal protein S6 kinase beta-1 and Aurora kinase B inhibit... 1 5
Neuropeptide Y receptor type 5 ligand 1-methylsulfonyl-N-(2-ph... 4 0
Tyrosine-protein kinase ZAP-70 inhibitor AGN-PC-07CO7Z family 1 0
Protein-tyrosine kinase 2-beta inhibitor 4-N-[(1R,2R)-2-(dimet... 1 0
Transient receptor potential cation channel subfamily V member... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

42616 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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