CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM17862
Family Name Cyclin-dependent kinase 4 and Cyclin-dependent kinase 2 inhibitor SureCN3575952 family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00444754 Functional Category Bioactive with Natural Product
Superfamily Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Binder Superfamily 3
Class Class 2356

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
Zucapsacin family 7 177
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Fatty-acid amide hydrolase 1 Inhibitor 3'-carbamoylbiphenyl-3-... 8 50
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
D(2) dopamine receptor Ligand Epidepride Family 31 66
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 55 36
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL14038... 1 9
Prelamin-A/C and Retinal dehydrogenase 1 inhibitor CHEMBL15810... 1 1
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 15 4
Cyclin-dependent kinase 4 and Cyclin-dependent kinase 1 inhibi... 1 11
Cyclin-dependent kinase 4 and Cyclin-dependent kinase 2 inhibi... 1 0
Muscarinic acetylcholine receptor M3 ligand N-[[3-[3-[(3-methy... 5 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00444755 CHEMBL489853 Bioactive SureCN13343907
CFAMM00444754 CHEMBL523780 Bioactive SureCN3575952

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26821 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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